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ations by assigning the prop

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Biology 2e
Biology 2e
2nd Edition
ISBN:9781947172517
Author:Matthew Douglas, Jung Choi, Mary Ann Clark
Publisher:Matthew Douglas, Jung Choi, Mary Ann Clark
Chapter3: Biological Macromolecules
Section: Chapter Questions
Problem 23CTQ: Amino acids have the generic structure seen below, where R represents different carbon-based side...
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Macmillan Learning Each ionizable group of an amino acid can exist in one of two states, charged or neutral. The electric charge on the functional group is determined by the relationship between its pK, and the pH of the solution. This relationship is described by the Henderson-Hasselbalch equation. Histidine has three ionizable functional groups. Complete the equilibrium equations by assigning the proper pK, for each ionization and the net charge on the histidine molecule in each ionization state. O H || H₂N-C-C-OH CH₂ + HN -NH PK₂=9.17 H H₂N-C- HN PK₁=7.59 CH₂ -NH -0- Answer Bank pk,= 1.8 +2 O H-L H₂N-C-C-O CH₂ -NH PK, = 6.0 -2 H H₂N-C-C-O 1 CH₂ +1 -NH 0
Transcribed Image Text:Macmillan Learning Each ionizable group of an amino acid can exist in one of two states, charged or neutral. The electric charge on the functional group is determined by the relationship between its pK, and the pH of the solution. This relationship is described by the Henderson-Hasselbalch equation. Histidine has three ionizable functional groups. Complete the equilibrium equations by assigning the proper pK, for each ionization and the net charge on the histidine molecule in each ionization state. O H || H₂N-C-C-OH CH₂ + HN -NH PK₂=9.17 H H₂N-C- HN PK₁=7.59 CH₂ -NH -0- Answer Bank pk,= 1.8 +2 O H-L H₂N-C-C-O CH₂ -NH PK, = 6.0 -2 H H₂N-C-C-O 1 CH₂ +1 -NH 0
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