b. Provide mechanisms and/or products for the following transformations. Pd°Ln, Cul, PhBr 1. HBpin, THF Et,N, THF H 2. Pd°Ln, PhBr, K3PO4, H2O/THF 3. The Mannich reaction can take many forms, including reactions where aromatic heterocycles are employed. Provide mechanisms for the reactions in the following sequence. Me Meo OMe MeN- MeN- N- MeN Br MeCN, 100 °C NaH, THF; Br H then 6M HCI MeO,C, -Me Me Meozc

b. Provide mechanisms and/or products for the following transformations. Pd°Ln, Cul, PhBr 1. HBpin, THF Et,N, THF H 2. Pd°Ln, PhBr, K3PO4, H2O/THF 3. The Mannich reaction can take many forms, including reactions where aromatic heterocycles are employed. Provide mechanisms for the reactions in the following sequence. Me Meo OMe MeN- MeN- N- MeN Br MeCN, 100 °C NaH, THF; Br H then 6M HCI MeO,C, -Me Me Meozc

Organic Chemistry: A Guided Inquiry

2nd Edition

ISBN:9780618974122

Author:Andrei Straumanis

Publisher:Andrei Straumanis

Chapter19: Eas: Electrophilic Aromatic Substitution

Section: Chapter Questions

Problem 45E

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