Based on the attached figure (Fig. 18.7B in the textbook), what would an increase in activation of D1 receptor-expressing spiny neurons in the striatum cause in downstream basal ganglia structures? Direct and indirect pathways Substantia D1 nigra pars D2 compacta (transient) Frontal cortex Cerebral cortex (transient) + (transient) + (transient) Caudate/putamen VA/VL complex of thalamus (transient) (transient) Globus pallidus, Globus pallidus, external segment internal segment 0 (tonic) (tonic) + (transient) Subthalamic nucleus OA. decreased activity in the globus pallidus external segment (GPe B. decreased activity in the cortex C. increased activity in the subthalamic nucleus (STN) D. decreased activity in the thalamus E. decreased activity in the globus pallidus internal segment (GPI) Parafascicular nucleus

Human Physiology: From Cells to Systems (MindTap Course List)
9th Edition
ISBN:9781285866932
Author:Lauralee Sherwood
Publisher:Lauralee Sherwood
Chapter7: The Peripheral Nervous System: Efferent Division
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Based on the attached figure (Fig. 18.7B in the textbook), what would an
increase in activation of D1 receptor-expressing spiny neurons in the striatum
cause in downstream basal ganglia structures?
Direct and indirect pathways
Substantia
D1
nigra
pars
D2
compacta
(transient)
Frontal cortex
Cerebral cortex
(transient)
+
(transient) +
(transient)
Caudate/putamen
VA/VL complex
of thalamus
(transient)
(transient)
Globus pallidus,
Globus pallidus,
external segment
internal segment
0
(tonic)
(tonic)
+
(transient)
Subthalamic
nucleus
OA. decreased activity in the globus pallidus external segment (GPe
B. decreased activity in the cortex
C. increased activity in the subthalamic nucleus (STN)
D. decreased activity in the thalamus
E. decreased activity in the globus pallidus internal segment (GPI)
Parafascicular
nucleus
Transcribed Image Text:Based on the attached figure (Fig. 18.7B in the textbook), what would an increase in activation of D1 receptor-expressing spiny neurons in the striatum cause in downstream basal ganglia structures? Direct and indirect pathways Substantia D1 nigra pars D2 compacta (transient) Frontal cortex Cerebral cortex (transient) + (transient) + (transient) Caudate/putamen VA/VL complex of thalamus (transient) (transient) Globus pallidus, Globus pallidus, external segment internal segment 0 (tonic) (tonic) + (transient) Subthalamic nucleus OA. decreased activity in the globus pallidus external segment (GPe B. decreased activity in the cortex C. increased activity in the subthalamic nucleus (STN) D. decreased activity in the thalamus E. decreased activity in the globus pallidus internal segment (GPI) Parafascicular nucleus
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