Be sure to answer all parts. Oseltamivir, the most effective antiviral drug against avian influenza currently available, can be prepared in 10 steps from shikimic acids. Identify the functional groups in Oseltamivir and shikimic acid. 1 HO,, 5 4 CO2H 10 steps 4 CO2CH,CH3 2 НО OH NH2 3 3

Chemistry
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Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
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Chapter22: Organic And Biological Molecules
Section: Chapter Questions
Problem 161CP
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Be sure to answer all parts.
Oseltamivir, the most effective antiviral drug against avian influenza currently available, can be
prepared in 10 steps from shikimic acids. Identify the functional groups in Oseltamivir and shikimic
acid.
1 HO,
4
.CO2H
10 steps
4
CO2CH,CH3
2 НО
2 N
H
ОН
NH2
3
3
Shikimic acid:
Group 1:
(select)
Group 2: (select)
Group 3:
(select)
Group 4:
(select)
Group 5: (select)
Oseltamivir:
Group 1: (select)
Group 2:
(select)
Group 3:
(select)
Transcribed Image Text:Be sure to answer all parts. Oseltamivir, the most effective antiviral drug against avian influenza currently available, can be prepared in 10 steps from shikimic acids. Identify the functional groups in Oseltamivir and shikimic acid. 1 HO, 4 .CO2H 10 steps 4 CO2CH,CH3 2 НО 2 N H ОН NH2 3 3 Shikimic acid: Group 1: (select) Group 2: (select) Group 3: (select) Group 4: (select) Group 5: (select) Oseltamivir: Group 1: (select) Group 2: (select) Group 3: (select)
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