B. Consider the following types of cells and their respective conditions: i. a yeast cell undergoing fermentation but with defective alcohol dehydrogenase (hint: In yeast, alcohol dehydrogenase is responsible for shuttling reducing equivalents of cytosolic NADH to the mitochondria.)* ii. a brain cell with non-functional Complex II of the electron transport chain* * Assume that the deficiency is isolated and will not influence the function of other respiration components In these cells/tissues, determine the following from the catabolism of the 2.5 moles of the disaccharide lactose (which will be hydrolyzed first to yield glucose and galactose). (Show complete solution) a. Net ATP from glycolysis b. ATP from oxidative decarboxylation (if applicable) c. ATP formed from Krebs cycle (if applicable) d. Total net ATP

Basic Clinical Laboratory Techniques 6E
6th Edition
ISBN:9781133893943
Author:ESTRIDGE
Publisher:ESTRIDGE
Chapter6: Basic Clinical Chemistry
Section6.5: Blood Glucose And Hemoglobin A1c
Problem 20RQ
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B. Consider the following types of cells and their respective conditions:
i. a yeast cell undergoing fermentation but with defective alcohol dehydrogenase (hint: In yeast,
alcohol dehydrogenase is responsible for shuttling reducing equivalents of cytosolic NADH to
the mitochondria.)*
ii. a brain cell with non-functional Complex II of the electron transport chain*
* Assume that the deficiency is isolated and will not influence the function of other respiration components
In these cells/tissues, determine the following from the catabolism of the 2.5 moles of the
disaccharide lactose (which will be hydrolyzed first to yield glucose and galactose). (Show
complete solution)
a. Net ATP from glycolysis
b. ATP from oxidative decarboxylation (if applicable)
c. ATP formed from Krebs cycle (if applicable)
d. Total net ATP
Transcribed Image Text:B. Consider the following types of cells and their respective conditions: i. a yeast cell undergoing fermentation but with defective alcohol dehydrogenase (hint: In yeast, alcohol dehydrogenase is responsible for shuttling reducing equivalents of cytosolic NADH to the mitochondria.)* ii. a brain cell with non-functional Complex II of the electron transport chain* * Assume that the deficiency is isolated and will not influence the function of other respiration components In these cells/tissues, determine the following from the catabolism of the 2.5 moles of the disaccharide lactose (which will be hydrolyzed first to yield glucose and galactose). (Show complete solution) a. Net ATP from glycolysis b. ATP from oxidative decarboxylation (if applicable) c. ATP formed from Krebs cycle (if applicable) d. Total net ATP
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