Phenylketonuria is a recessive autosomal genetic disorder that can cause mental retardation. Phenylketonuria is particularly common in Turkey, where 1 in 2600 children are born with the disease. As of 2011, the population of Turkey was 73.6 million. Based on this data, and assuming that the Turkish population is in Hardy-Weinberg equilibrium. (a) Estimate the number of carriers of phenylketonuria in Turkey (b) Estimate the proportion of unaffected individuals who are carriers.

Human Heredity: Principles and Issues (MindTap Course List)
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Chapter19: Population Genetics And Human Evolution
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Problem 9QP: Using the HardyWeinberg Law in Human Genetics Suppose you are monitoring the allelic and genotypic...
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Phenylketonuria is a recessive autosomal genetic disorder that can cause mental retardation. Phenylketonuria is particularly common in Turkey, where 1 in 2600 children are born with the disease. As of 2011, the population of Turkey was 73.6 million. Based on this data, and assuming that the Turkish population is in Hardy-Weinberg equilibrium.

(a) Estimate the number of carriers of phenylketonuria in Turkey

(b) Estimate the proportion of unaffected individuals who are carriers.

 

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