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Question 15 The higher protein abundance observed in the ACE20E allele compared to the wild- type (ACE2*) allele is caused by altered regulation of gene expression at the post- transcriptionalL level. Which of the following mechanisms are a likely explanation for the abnormally high protein expression from the ACE20E allele? Select all that apply C Increased length of the poly-A tail increases mRNA stability and translational efficiency Alternative splicing makes a shorter protein that is translated faster Faster 5' capping increases MRNA stability and translational efficiency Decreased microRNA expression reduces translational inhibition and ACE2 MRNA degradation All of the above mechanisms are likely explanations

Question 15 The higher protein abundance observed in the ACE20E allele compared to the wild- type (ACE2*) allele is caused by altered regulation of gene expression at the post- transcriptionalL level. Which of the following mechanisms are a likely explanation for the abnormally high protein expression from the ACE20E allele? Select all that apply C Increased length of the poly-A tail increases mRNA stability and translational efficiency Alternative splicing makes a shorter protein that is translated faster Faster 5' capping increases MRNA stability and translational efficiency Decreased microRNA expression reduces translational inhibition and ACE2 MRNA degradation All of the above mechanisms are likely explanations

Human Anatomy & Physiology (11th Edition)
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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Question 15 The higher protein abundance observed in the ACE20E allele compared to the wild- type (ACE2*) allele is caused by altered regulation of gene expression at the post- transcriptionalL level. Which of the following mechanisms are a likely explanation for the abnormally high protein expression from the ACE20E allele? Select all that apply C Increased length of the poly-A tail increases mRNA stability and translational efficiency Alternative splicing makes a shorter protein that is translated faster Faster 5' capping increases MRNA stability and translational efficiency Decreased microRNA expression reduces translational inhibition and ACE2 MRNA degradation All of the above mechanisms are likely explanations
Transcribed Image Text:Question 15 The higher protein abundance observed in the ACE20E allele compared to the wild- type (ACE2*) allele is caused by altered regulation of gene expression at the post- transcriptionalL level. Which of the following mechanisms are a likely explanation for the abnormally high protein expression from the ACE20E allele? Select all that apply C Increased length of the poly-A tail increases mRNA stability and translational efficiency Alternative splicing makes a shorter protein that is translated faster Faster 5' capping increases MRNA stability and translational efficiency Decreased microRNA expression reduces translational inhibition and ACE2 MRNA degradation All of the above mechanisms are likely explanations
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