Bob has XXY chromosomes (Klinefelter syndrome) and is color blind. His mother and father have normal color vision, but his maternal grandfather is color blind. Assume that Bob’s chromosome abnormality arose from nondisjunction in meiosis. In which parent and in which meiotic division did nondisjunction take place? Assume no crossing over has taken place. Explain your answer.

Human Heredity: Principles and Issues (MindTap Course List)
11th Edition
ISBN:9781305251052
Author:Michael Cummings
Publisher:Michael Cummings
Chapter6: Cytogenetics: Karyotypes And Chromosome Aberrations
Section: Chapter Questions
Problem 16QP: Assume that a meiotic-nondisjunction event causes trisomy 8 in a newborn. If two of the three copies...
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Bob has XXY chromosomes (Klinefelter syndrome) and is color blind.
His mother and father have normal color vision, but his maternal
grandfather is color blind. Assume that Bob’s chromosome abnormality
arose from nondisjunction in meiosis. In which parent and in which
meiotic division did nondisjunction take place? Assume no crossing
over has taken place. Explain your answer.

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