Strong support for the mechanism of the nucleophilic aromatic substitutionreaction that proceeds through a benzyne intermediate comes from the reaction shown here, in which bromobenzene is treated with KNH2 in the presence of cyclopentadiene. A product that is isolated has the formula C11H10. Draw the structure of that product and explain how it validates the production of a benzyne intermediate. BrKNH2C11H10

Bromobenzene will react with KNH2 to give the benzyne intermediate which will further react with the…

Answered: Br KNH2 C11H10

Introduction to General, Organic and Biochemistry

11th Edition

ISBN:9781285869759

Author:Frederick A. Bettelheim, William H. Brown, Mary K. Campbell, Shawn O. Farrell, Omar Torres

Publisher:Frederick A. Bettelheim, William H. Brown, Mary K. Campbell, Shawn O. Farrell, Omar Torres

Chapter22: Proteins

Section: Chapter Questions

Problem 22.67P

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Strong support for the mechanism of the nucleophilic aromatic substitution
reaction that proceeds through a benzyne intermediate comes from the reaction shown here, in which bromobenzene is treated with KNH₂ in the presence of cyclopentadiene. A product that is isolated has the formula C₁₁H₁₀. Draw the structure of that product and explain how it validates the production of a benzyne intermediate.

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