Briefly describe the difference between agonist and antagonists. What is a difference comparing to allosteric modulators?

Human Physiology: From Cells to Systems (MindTap Course List)
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Chapter6: The Peripheral Nervous System: Afferent Division; Special Senses
Section6.2: Pain
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  1. Briefly describe the difference between agonist and antagonists. What is a difference comparing to allosteric modulators?
  2. What are major factors that alter pharmacokinetics in elderly? Give some examples.
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