Define an opioid agonist, antagonist, mixed agonist-antagonist, and partial agonist. Give an example of each and how they are therapeutically useful.
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Define an opioid agonist, antagonist, mixed agonist-antagonist, and partial agonist. Give an example of each and how they are therapeutically useful.
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- Describe the difference between drugs that are agonists and those that are antagonists.Methamphetamine "highs" are often followed with psychiatric-like behavioural abnormalities. Is methamphetamine an agonist or antagonist in nature?Briefly define the mechanism of analgesic action of morphine? explain at your own words
- The endogenous ligand for an ion channel causes the influx of 50 Na+ ions per second. This ion channel has constitutive activity of 10 Na+ ions per second. If drug A binds to the ion channel and causes the influx of 50 Na+ ions per second, which of the following categories best describes drug A? Group of answer choices full agonist antagonist partial agonist inverse agonistIdentify examples of drugs classified as nonopioids, nonsteroidal antiinflammatory drugs, opioids (opioid agonists, opioids with mixed actions, opioid agonists-antagonists and antagonists), and miscellaneous drugs.How does the drugs can be classified based on their effects on receptors: full agonist, partial agonist, inverse agonist, antagonist (competitive, non-competitive, etc.).
- What happens to an agonist's efficacy ("maximum effect") and potency (potency) in the presence of a reversible, competitive antagonist? Select an option: a.NothingEfficacy is unchanged, power is increased b.Efficacy is decreasing, power is unchanged c.Efficacy is increasing, power is unchanged d.Efficacy is unchanged, power is decreasingWhat is the relationship between the action of salicylate or aspirin that researchers believe accounts for some of its therapeutic effects?Methamphetamine “highs” often are accompanied by behavioral changes that resemble schizophrenia. Does methamphetamine act as an agonist or antagonist?