CD62L CCR7 CXCR5 S1P1 Naïve T and B cells would not home properly to the HEV. Naïve T cells would not home properly to the paracortex. Activated B cells would not home properly to the follicle-paracortex border. The animal would be immunocompromised and not be able to develop adaptive immune responses unless compensated by other chemokines. Naïve B cells would not home properly to the follicle. The animal would be partially, but significantly, immunocompromised because it would not be able to develop T cell-dependent antibody responses unless compensated by other chemokines. Naïve T and B cells, effector T and B cells, and effector memory T and B cells would not be able to leave the lymph node. Answer Bank The animal would be significantly immunocompromised but may be able to compensate with some innate immunity and splenic T cell and B cell activity. The animal would be immunocompromised unless compensated by other egress regulators and extralymphoid immune cell activity.
CD62L CCR7 CXCR5 S1P1 Naïve T and B cells would not home properly to the HEV. Naïve T cells would not home properly to the paracortex. Activated B cells would not home properly to the follicle-paracortex border. The animal would be immunocompromised and not be able to develop adaptive immune responses unless compensated by other chemokines. Naïve B cells would not home properly to the follicle. The animal would be partially, but significantly, immunocompromised because it would not be able to develop T cell-dependent antibody responses unless compensated by other chemokines. Naïve T and B cells, effector T and B cells, and effector memory T and B cells would not be able to leave the lymph node. Answer Bank The animal would be significantly immunocompromised but may be able to compensate with some innate immunity and splenic T cell and B cell activity. The animal would be immunocompromised unless compensated by other egress regulators and extralymphoid immune cell activity.
Human Heredity: Principles and Issues (MindTap Course List)
11th Edition
ISBN:9781305251052
Author:Michael Cummings
Publisher:Michael Cummings
Chapter17: Genes And The Immune System
Section: Chapter Questions
Problem 31QP
Related questions
Question
Immunology help
![CD62L
CCR7
CXCR5
S1P1
Naïve T and B cells would not
home properly to the HEV.
Naïve T cells would not home
properly to the paracortex.
Activated B cells would not
home properly to the
follicle-paracortex border.
The animal would be
immunocompromised and not be
able to develop adaptive
immune responses unless
compensated by
other chemokines.
Naïve B cells would not home
properly to the follicle.
The animal would be partially,
but significantly,
immunocompromised because it
would not be able to develop T
cell-dependent antibody
responses unless compensated
by other chemokines.
Naïve T and B cells, effector T
and B cells, and effector
memory T and B cells would not
be able to leave the lymph node.
Answer Bank
The animal would be significantly immunocompromised but may be able to compensate with some innate immunity and splenic T cell and B
cell activity.
The animal would be immunocompromised unless compensated by other egress regulators and extralymphoid immune cell activity.](/v2/_next/image?url=https%3A%2F%2Fcontent.bartleby.com%2Fqna-images%2Fquestion%2Fc3eb3c55-3996-4e07-93a0-a3410210cd33%2F248e0e9d-43d4-4116-a212-6203235f18c8%2Fk8i6a1_processed.png&w=3840&q=75)
Transcribed Image Text:CD62L
CCR7
CXCR5
S1P1
Naïve T and B cells would not
home properly to the HEV.
Naïve T cells would not home
properly to the paracortex.
Activated B cells would not
home properly to the
follicle-paracortex border.
The animal would be
immunocompromised and not be
able to develop adaptive
immune responses unless
compensated by
other chemokines.
Naïve B cells would not home
properly to the follicle.
The animal would be partially,
but significantly,
immunocompromised because it
would not be able to develop T
cell-dependent antibody
responses unless compensated
by other chemokines.
Naïve T and B cells, effector T
and B cells, and effector
memory T and B cells would not
be able to leave the lymph node.
Answer Bank
The animal would be significantly immunocompromised but may be able to compensate with some innate immunity and splenic T cell and B
cell activity.
The animal would be immunocompromised unless compensated by other egress regulators and extralymphoid immune cell activity.
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