ChemistryGiven TETRAPEPTIDE: Prolinyl-Argininyl-Cysteinyl-TryptophanPredict the direction of the peptide in electrophoresis at pH 7 and pH11.5. (Use table on the upper right for the estimated pK values of some functional groups). iven the tetrapeptide:O=HNHNH₂CNHCH₂CH₂CH₂0=HOCH₂SH•NHU ONH6Dissociating Groups in Proteins pk Rangea-carboxyl groupa-amino groupNon a-COOH of Asp or GluSoftSulhydryl of CysteineHydroxyl of TyrosineImidazole of His&-Amino of LysineGuanidine of Arginine2.0104.08.510.06.510.412.0

The given peptide according to the given sequence is: Proline makes the N terminal of the peptide.…

Answered: Chemistry Given TETRAPEPTIDE:…

Introductory Chemistry: A Foundation

9th Edition

ISBN:9781337399425

Author:Steven S. Zumdahl, Donald J. DeCoste

Publisher:Steven S. Zumdahl, Donald J. DeCoste

Chapter21: Biochemistry

Section: Chapter Questions

Problem 8QAP

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Chemistry

Given TETRAPEPTIDE: Prolinyl-Argininyl-Cysteinyl-Tryptophan

Predict the direction of the peptide in electrophoresis at pH 7 and pH11.5. (Use table on the upper right for the estimated pK values of some functional groups).

iven the tetrapeptide:
O=
HN
H
NH₂
C
NH
CH₂
CH₂
CH₂
0=
H
O
CH₂
SH
•N
H
U O
NH
6
Dissociating Groups in Proteins pk Range
a-carboxyl group
a-amino group
Non a-COOH of Asp or Glu
Soft
Sulhydryl of Cysteine
Hydroxyl of Tyrosine
Imidazole of His
&-Amino of Lysine
Guanidine of Arginine
2.0
10
4.0
8.5
10.0
6.5
10.4
12.0

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