The following conformation for the cyanoguanidine group of cimetidine is not favored due to unfavorable steric interactions. CN H. N' Me Which of the following diagrams depicts the unfavorable interaction? CN N- CN N- H H. 'N. N-CN H, N. N 'N' H H R Me Me R Me A C O C O B O D O A ZIR

The following conformation for the cyanoguanidine group of cimetidine is not favored due to unfavorable steric interactions. CN H. N' Me Which of the following diagrams depicts the unfavorable interaction? CN N- CN N- H H. 'N. N-CN H, N. N 'N' H H R Me Me R Me A C O C O B O D O A ZIR

Organic Chemistry

9th Edition

ISBN:9781305080485

Author:John E. McMurry

Publisher:John E. McMurry

Chapter11: Reactions Of Alkyl Halides: Nucleophilic Substitutions And Eliminations

Section11.SE: Something Extra

Problem 40AP: The following Walden cycle has been carried out. Explain the results, and indicate where Walden...

See similar textbooks

Related questions

Q: Aqueous sulfuric acid (H,SO,) will react with solid sodium hydroxide (NaOH) to produce aqueous sodiu...

Q: 5. Water flowing through a garden hose of diameter 2.74 cm fills a 25.0-L bucket in 1.50 min. a. Wha...

A: Diameter = 2.74 cm Volume = 25.0L Time = 1.50 min

Q: II. Problem Solving 1. A hollow cylindrical copper pipe is 1.50 m long and has an outside diameter o...

Q: behind the paper, eral Problems For each of the following compounds, draw an isomer that has the sam...

A: Isomerism : The compounds which are having same molecular formula but differ in their properties ...

Q: What is the mass % of carbon in dimethylsulfoxide (C2H;SO)? (C= 12.011 amu, H = 1.008 amu, S = 32.06...

A: The % of carbon in dimethylsulfoxide (C2H6SO) is: Atomic masses of C = 12.011 amu, H = 1.008 amu, S ...

Q: Find the mass of a solid gold rectangular bar that has dimensions of 6.35 cm x 12.5 cm x 33.3 cm. 4....

Q: For the gas phase isomerization of cis-1,2-diphenylethene, cis-CGHSCH=CHC,Hstrans-C6H5CH=CHC6H5 the ...

Q: Hepten-2-one is a ketone that also contains a C=C double bond between carbons 6 and 7. If this subst...

A: Alkene is reduced to give alkanes using Pt as a catalyst in presence of H2.

Q: Choose the correct hybridization for the atom indicated in the molecule below. CH 3CH 2CH 2CH 3 sp2 ...

Q: Question 18 The cell notation for the Galvanic cell is Cd(s)/Ca2*2(s)/" The Standard Reduction Poten...

Q: Consider the reaction: BaSO4 Ba2+ + SO42-; Ksp = 1.1 x 10-10 .What is ΔG° at 25 °

A: Using the relationship between Gibbs free energy and equilibrium constant, □G° = -RT×ln(Ksp) T = 25...

Q: a) CH3-CH2 CH2-CH3 b) CH3 -CH2-CH=CH-CH2-CH3

A: Step1- first identify the longest carbon chain. Step2- start numbering from that side such that sen...

Q: 3. Complete the following equations for the addition of an acid and base to phosphate buffer solutio...

A: Quick summery: a) In acidic solution phosphare buffer act as base and abstract proton. b) In basic...

Q: v Draw Lewis structures for each of the following. Give the total number of valence electrons, selec...

A: Lewis dot structure of molecule can be predicted by using the octet rule where if valance electron e...

Q: What are the variables in a van’t Hoff plot? K vs T K vs 1/T ln K vs 1/T ln ...

A: To explain: The variables in a van't Hoff plot.

Q: A chemist prepares a solution of silver(I) nitrate AgNO3 by measuring out 210.μmol of silver(I) ni...

Q: 2 CO(g) + O2(g) +2 CO2(3) K = 6.1 x 105 If [CO] = 0.00100M and [O2] = 0.00127 M, determine [CO2], in...

A: The given balanced chemical reaction is: 2 CO(g) + O2(g) <--------------> 2 CO2(g) The Kc expr...

Q: what is the half life of the kinetic isomer in days

A: The data given is,

Q: General Problems 3-48 For each of the following compounds, draw an isomer that has the same function...

A: The compounds given are,

Q: Gaseous butane (CH. (CH, (CH,), CH,) will react with gaseous oxygen (0,) to produce gaseous carbon d...

A: Butane reacts with oxygen to form carbon dioxide and water. The equation for the balanced chemical r...

Q: How many molecules are present in 300.0 g of benzaldehyde (C_{6}*H_{5} * C * H * O)

Q: The AG°rxn for the reaction: N2(g) + O2(g) 2 NO(g) is +173 kJ/mol at 25 °C. What is the equilibrium ...

Q: In the laboratory a student measures the percent ionization of a 0.429 M solution of formic acid , H...

Q: Each row of the table below describes an aqueous solution at about 25°C . Complete the table. That...

A: • The values provided in the question are:- i) Hydronium ion concentration of solution A, [H3O+] ...

Q: 1. Describe the operation of spectrophotometer.

Q: Hydrogen sulfide and oxygen react to form sultur dioxide and water, Ilike this! 2H,S(g)+30,(g) 2s0, ...

Q: The height of the column in a mercury barometer is independent of the A. Atmospheric pressure C. Dia...

A: Given: To explain to independency of the height of the column in a mercury barometer.

Q: n biological systems, an ACTIVE transport process is one in which an important chemical component is...

A: Since you have posted multiple questions as per guidelines we can answer only one per session . If y...

Q: Molecular Formula:C6H1202, EOU = IR (cm-1): 2951 bond 1743 bond Fill-up this > M+ (m/z) 1H NMR (ppm)...

A: C6H12O

Q: What is the concentration (M) of KCl in a solution made by mixing 25.0 mL of 0.100 M KCl with 50.0 m...

Q: 15) Which one of the compounds corresponds to this IR spectrum. NH2 1000 2000 3000 4D00

Q: Was there any physical change in the characteristics of trichloroethane when it was added to water?

A: Trichloroethane is micible in water. When it is added to water there is no any physical change.

Q: Consider the reaction: N204(g) 2 NO2(g). What is AS° at 25 °C? AHP, KJ mol-1 AGf, KJ mol-1 NO2 33.85...

A: T = 25 0C = 298.15 K (Temperature in K = Temperature in 0C + 273.15 ) For NO2 : ∆Gf° = ∆Hf° - T∆S°...

Q: 2. Discuss the different factors that affect the absorbance of a solution.

A: Absorbance is affected by a several factor .eg,light,solution ,temperature ,pH etc

Q: Determine the half life of the second order reaction, 2A -> product, given the initial concentration...

A: For the second-order reaction, the sum of the exponents in the rate law is two. The rate of second-o...

Q: What is the purpose of the salt bridge in an electrochemical cell? To maintain electroneutrali...

A: Below attached file showing the details answer. All the best.

Q: Which of the following is/are TRUE about Galvanic cell? The Gibbs Free Energy of the cell is negati...

A: For spontaneous process Gibbs free energy change in negative...

Q: dified True or False tions: Write CHEMISTRY if the statement is correct, if otherwise, change the un...

Q: Determine the concentration of 7.13 g zinc nitrate (MW = 189.4 g/mol) dissolved in 200.0 mL distille...

A: The solution is as follows:

Q: EXPERIMENT: DETERMINING HEAT OF REACTION Why do we want to have mostly ice and only a little wat...

A: We want to have mostly ice and only a little water (about 75% ice to 25% water) in the small beaker ...

Q: Question 6 The equilibrium constant for a reaction A +B = Y + Z is 0.1. What amount of A must be mix...

Q: トyPo + 2 HNog (Cz Hs ) Be e + Be CH3)2 M9 Et, + t-BUOH-

A: Since you have posted questions with multiple subparts, we are entitled to answer the first 3 only. ...

Q: 3-38 Give IUPAC names for the following compounds: (a) CH3 (b) CH3 (c) H3C CH3 CH3CHCH2CH2CH3 CH3CH2...

A: According to IUPAC nomenclature first we have to select the longest chain of hydrocarbon which conta...

Q: At equilibrium, what is the value of ΔGrxn? < 1 < 0 = 1 = 0

A: Answer At equilibrium, value of ∆Grxn We know that For spontaneou...

Q: What is the cell potential for the following reaction at 25 °C? Ni(s) + Cu2*(0.010 M) → Ni2*(0.0010 ...

A: The answer is given below

Q: Why does liquid water have higher Einternal than ice at the same temperature?

A: We would discuss the factors which affect internal energy.

Q: In a first-order reaction, the half-life is 137 minutes. What is the rate constant? O 1.22 x 10-4 s-...

A: The rate constant and half life of first order reaction is related as follows - Half-life = 0.693/k

Q: Which of the following factors affects the equilibrium of reversible reactions involving gas? O conc...

A: Equilibrium Reactions: The chemical reactions that can come back to the original path in which it ha...

Q: Consider the reaction A+B+CD The order of the reaction with respect to each reactant is given below:...

A: Given the order of the reaction with respect to A, B and C are respectively 1, 1, and 0. Hence the ...

Q: Calculate the mass of CO, (gram-formula mass-4401 g/mol) produced when 0.64 kg of cellulose is compl...

A: Given, The mass of CO2 (gram-formula mass-4401 g/mol) produced when 0.64 kg of cellulose is complete...

Concept explainers

Coordination Chemistry

It is a part of chemistry, in which the study of compounds that have central atoms surrounded by molecules or ions, known as ligand, is known as coordination chemistry.

Question

The following conformation for the cyanoguanidine group of cimetidine is not favored due to
unfavorable steric interactions.
CN
H.
N'
Me
Which of the following diagrams depicts the unfavorable interaction?
CN
N-
CN
N-
H
H.
'N.
N-CN
H,
N.
N
'N'
H
H
R
Me
Me
R
Me
A
C
O C
O B
O D
O A
ZIR

Expert Solution

This question has been solved!

Explore an expertly crafted, step-by-step solution for a thorough understanding of key concepts.

SEE SOLUTION Check out a sample Q&A here

Step 1

VIEW

Step 2

VIEW

Step by step

Solved in 2 steps with 2 images

SEE SOLUTION Check out a sample Q&A here

Knowledge Booster

Learn more about

Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, chemistry and related others by exploring similar questions and additional content below.

Similar questions

Make an electron-flow-mechanism for this synthetic scheme. This involves predicting major and by-products using electronic and structural effects. The arrow push mechanism must be shows. (from the reaction of α-ketoacids and oxaprolines to proteins that contain native serine residues)
please provide the machanisms of 1a, 1e, 1f
it's for the Catalytic Hydrogenation of trans-p-Anisalacetophenone experiment.
Using the template structure of sesamin below, label the sets of equivalent hydrogens as H1, H2, H3, etc.
Show hoe the Cahn-Ingold-Prelog sequence rules are used to assign the configuration of the stereogenic centre as either R or S. Please answer this for me
Please explain the significance of Wohler’s synthesis of urea in his lab without copying from the internet. No plagiarism, please. Also, please write legibly and clearly too. Thank you.
Suppose we aempt the conversion of fumaric acid to deuterated malic acid with BD3·THF,followed by oxidation with D2O2in NaOD(aq). Show all the possible stereoisomers (as Fisherprojections) that may be formed, and draw the mechanistic pathways (showing stereochemistry)that lead to these possible products
Name the following and include any E/Z stereochem in the name .
Calculate ΔSsys° (J/K) for the catalytic hydrogenation of acetylene to ethane: C2H2(g) + H2(g) → C2H4(g) Substance S° (J/K·mol) C2H2(g) 200.8 H2(g) 130.58 C2H4(g) 219.4
Solve for the Keq of these 2 successive reactions at 25C. (Glcose-1-phspte to glcose-6-phspte G'= -1.75Kcal) (Glcose-6-phsphte to frctose-6-phspate G'= -0.40Kcal) at pH7
What is the correct order of reactivity of CH3CHO, C2H5COCH3 and CH3COCH3?
A scientist is doing a Fischer Esterfication using methanol that was isotopically labeled 18O (indicated by the 18 as an asterisk). Based off of the possible products in the image, which one will form. I need help answering this using structures and mechanisms.