CHM 2 125 LABORATORY MANUAL 4. Draw the structures of the product of the reaction of each of the organometallics below with acetophenone (CH;C(O)C,Hs). a. butyllithium b. phenylmagnesium bromide c. lithium dicyclohexylcuprate(I) 5. Draw the structures of the product of the reaction of an excess of each of the organometallics below with benzoic acid (C,H5COOH) (you may need to look up the reaction in the chapter on carboxylic acids). a. butyllithium b. phenylmagnesium bromide c. lithium dicyclohexylcuprate(I) 6. In the MS spectrum of the product of this experiments (benzaldehyde + allylzinc bromide) identify the fragments at m/e = 148, 130, 107. 7. The reaction of allyllithium with the aldehyde shown gives the indicated product. Show how the observed product was formed (mechanism). CО-CН3 1. Allyllithium CHO 2. H', Н,О

CHM 2 125 LABORATORY MANUAL 4. Draw the structures of the product of the reaction of each of the organometallics below with acetophenone (CH;C(O)C,Hs). a. butyllithium b. phenylmagnesium bromide c. lithium dicyclohexylcuprate(I) 5. Draw the structures of the product of the reaction of an excess of each of the organometallics below with benzoic acid (C,H5COOH) (you may need to look up the reaction in the chapter on carboxylic acids). a. butyllithium b. phenylmagnesium bromide c. lithium dicyclohexylcuprate(I) 6. In the MS spectrum of the product of this experiments (benzaldehyde + allylzinc bromide) identify the fragments at m/e = 148, 130, 107. 7. The reaction of allyllithium with the aldehyde shown gives the indicated product. Show how the observed product was formed (mechanism). CО-CН3 1. Allyllithium CHO 2. H', Н,О

Organic Chemistry

9th Edition

ISBN:9781305080485

Author:John E. McMurry

Publisher:John E. McMurry

Chapter9: Alkynes: An Introduction To Organic Synthesis

Section9.SE: Something Extra

Problem 52AP

See similar textbooks

Similar questions

The Zeisel method is an old analytical procedure for determining the number of methoxyl groups in a compound. A weighed amount of the compound is heated with concentrated HI, ether cleavage occurs, and the iodomethane product is distilled off and passed into an alcohol solution of AgNO3, where it reacts to form a precipitate of silver iodide. The Agl is then collected and weighed, and the percentage of methoxyl groups in the sample is thereby determined. For example, 1.06 g of vanillin, the material responsible for the characteristic odor of vanilla, yields 1.60 g of Agl. If vanillin has a molecular weight of 152, how many methoxyl groups does it contain?
1. What type of reaction is occuring in step 3? (halogenation, hydrohalogenation, reduction, keto–enol tautomerism, dehydrohalogenation, acid-catalyzed hydration, base-catalyzed hydration) 2. Which reagent is necessary for step 3? (Br2, HBr, H2/Pt, NaNH2, H20/H2SO4/HgSO4)
1.Label kinetic product 2.Label the thermodynamic product 3.Predict the four products from reaction of alkene with one equivalent HBr
In which compound is the halogen substituted most rapidly by aq hydroxide ions? a. CH3CH2CH2CH2Cl b. (CH3)3CI c. (CH3)3CCl d. CH3CH2CH2CH2I
A benzene ring reacts with these reagents in order: 1) Cl2, AlCl3 2) Mg 3) CH3CH2CHO 4) H + 5) conc. H2SO4, heat, -H2O I am confused about what happens after the first step.
Arrange the alkyl halides in order of increasing reactivity in an SN2 reaction with KI in acetone (least first). I, IV, III, II II, III, I, IV IV, I, III, II III, II, IV, I
1) What is the major product generally formed when a tertiary alkyl bromide (R3Br) reacts with sodium methoxide in methanol? 2) How is this major product formed?
2. How many substitution product/s is/are formed when metabromo anisole is treated with ammonia?A. 0-no reactionB. 1C. 2D. 3
Rank the following in increasing order of reactivity towards nucleophilic acyl substitutiona. CH3COCl, CH3COOCH3, CH3CONH2b. CH3COOCH3, CH3COOCH2CCl3, CH3COOCH(CF)3
organic chemistry 6) Aniline NH₂ is best prepared by
Triethyloxonium tetrafluoroborate, (CH3CH2)3O+ BF4 −, is a solid with melting point 91–92 °C. Show how this reagent can transfer an ethyl group to a nucleophile (Nuc:−) in an SN2 reaction. What is the leaving group? Why might this reagent be preferred to using an ethyl halide?
These reagents can produce ketones with alkynes A. BH3, THF, H2O2 B. KMnO4 C. O3 D. H2SO4, H2O, HgSO4