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- Does the phenotype indicated by the red circles and squares in this pedigree show an inheritance pattern that is autosomal dominant, autosomal recessive, or X-linked?Given the following pedigree: Is the trait autosomal or sex-linked? Is the trait dominant or recessive? Based only on the information given, what is the probability that I-2 is heterozygous? Give the genotypes of individuals II-3, II-4. What is the probability that individual III-1 is purebreeding?Using the pedigree chart attached: Above is a pedigree for colorblindness. Based on the pedigree, is the disease dominant or recessive and is it sex-linked or autosomal? Why? Furthermore, what is the probability that 18 on this chart is affected but the condition, and what is the probability that 18 is a carrier? Why? Are the probability of being a carrier and an affected individual different? Why?
- In pedigrees, individuals are usually specified by using a Roman numeral for their generation in the chart and an Arabic number for their position (reading left to right) within that generation. If we use the letter c for the allele that causes cystic fibrosis, what are the genotypes of individuals III-3 and III-4 (the third and fourth individuals shown in generation III) in the pedigree that shows this disease?The following pedigree shows the inheritance of Huntington’s disease, a fatal genetic disorder that causes neurodegeneration. Since signs and symptoms usually do not appear until adulthood, many who are carriers may not realize their risk of passing on the disease-causing allele. The following pedigree represents a family in which some people are affected by Huntington’s disease. Using just the information on this pedigree, is Huntington’s disease caused by a dominant allele or recessive alleles? What are the genotypes of the grandparents (I-1 and I-2)? What are the genotypes of the parents (II-6 and II-7)? If the parents above have another child, what is the chance that they will be affected by the Hungtington’s disease allele? What are the genotypes of the unaffected children (III-8, 9, 10)? What is the chance that the unaffected children above will pass on a Huntington’s disease allele to their children? What is the genotype of the affected child (III-11)? What is the chance…For this pedigree, give the most likely mode of inheritance, assuming that the trait is rare. For the pedigree, what is the probability that III-4 and III-5 will have a boy AND he will be affected?
- what is the probability that a couple (both heterozygous for the same recessive mutation) will have two children with the disease if the couple plans to have four children in total?The three genes X, Y, and Z are linked on an autosomal chromosome in humans (X to Y is 15 cM, and Y to Z is 18 cM). If an individual that is heterozygous at all three loci (XYZ/xyz) has children with an individual that is homozygous recessive at all three loci (xyz/xyz), what is the probability that they will have a child that is phenotypically identical to either parent (X-Y-Z- or xxyyzz)? Assume there is no genetic interference to double crossover events at this site.Given the pedigree below: Is the trait dominant or recessive? What are the most likely genotypes of individuals I-1 and I-2? What is the probability that individual II-2 is a carrier?
- Using the given pedigree chart, suppose individuals III-1 and III-2 are expecting their sixth child. What is the chance (percent) that the sixth child will have the sickle cell trait? The given pedigree chart corresponds with generational cystic fibrosis. If individuals III-2 and III-3 were to have a second child, what is the probability that their second child will have cystic fibrosis? Read the following family history and draw a pedigree to determine the inheritance pattern for achondroplasia. Once the pedigree is assembled , label the genotypes of each individual using a capital "A to represent the dominant allele and a lower case "a " to represent the recessive allele and create a key to identify which version is the achondroplasia allele. If you are unsure of the genotype , label the individual with a "" in place of the unknown allele. Family History : Jada and Noel , both of short stature, have been married for twenty years. They have three children : an eighteen - year-old boy named Shawn , of short stature ; a fifteen- year- old boy named John , of short stature ; and a twelve -year -old girl named Ann , of average height Noel and Jada also had a male child bom with severe achondroplasia who died six months after birth from respiratory failure . Noel's father was of short stature , while his mother was average height . Noel has a brother and a…