Clostridium difficile infection is the leading causeof hospital-associated gastrointestinal illness. It is typicallytreated with a course of antibiotics, but the infection recursin about 20% of cases. C. difficile infections are difficult toeradicate because the bacteria exist in two forms: a repli-cating, toxin-producing form and a spore form that is resis-tant to antibiotics. Fecal microbiota transplantation—thetransfer of normal gut microbiota from a healthy individ-ual—can resolve >90% of recurrent infections, a much bet-ter cure rate than further antibiotic treatment alone. Whydo you suppose microbiota transplantation is so effective?

Clostridium difficile infection is the leading causeof hospital-associated gastrointestinal illness. It is typicallytreated with a course of antibiotics, but the infection recursin about 20% of cases. C. difficile infections are difficult toeradicate because the bacteria exist in two forms: a repli-cating, toxin-producing form and a spore form that is resis-tant to antibiotics. Fecal microbiota transplantation—thetransfer of normal gut microbiota from a healthy individ-ual—can resolve >90% of recurrent infections, a much bet-ter cure rate than further antibiotic treatment alone. Whydo you suppose microbiota transplantation is so effective?

Aquaculture Science

3rd Edition

ISBN:9781133558347

Author:Parker

Publisher:Parker

Chapter11: Health Of Aquatic Animals

Section: Chapter Questions

Problem 5KA

See similar textbooks

Similar questions

In 2005, J. Robin Warren and Barry J. Marshall shared theNobel Prize in Medicine for discovering the bacteriumHelicobacter pylori and for establishing experimental proofthat it plays a major role in gastritis and peptic ulcer disease.The story began when Warren, a pathologist, noticed thatbacilli were associated with the tissues taken from patientssuffering from ulcers. Look up the history of this case and describeWarren’s first hypothesis. What sorts of evidence did ittake to create a credible theory based on it?
which organism most easily causes an infection? a. shigella - ID50-10 b. legionella pnemiphila - ID20-1 c. E.coli 0156-20 d. Treponema pallidum - ID50-57 e. can't tell
A pathogenic bacterium’s toxin causes symptoms thatincrease the bacterium’s chance of spreading from hostto host. Does this information indicate whether thepoison is an exotoxin or endotoxin? Explain.
Functionally, normal microbiota is beneficial to it's host organism and on the other hand, it may cause harm, How does this normal microbiota cause harm? Explain briefly but acurately
An outbreak of Methicillin-resistant Staphylococcus aureus (MRSA) in the surgical ward at the hospital forces the hospital administrator to cancel and postpone all non-essential surgeries until the source of infection has been located and for measure put into place. Bacterial samples obtained from swab of wad staff equipment and surfaces arr brought to the lab for analysis. 1. What testing method will you employ to determine the level of exposure? 2 How would a positive test present? 3. How would a negative test present? 4. What recommendations would you make in your report?
Explain each of the following:a. why the clinical signs of infection are notpresent immediately after the microorganismenters the bodyb. why infection can often be cured without drugtreatmentc. why antibacterial agents might be prescribedfor an infection
Why has the success of fecal transplants in treatingC. difficile infection encouraged the development ofecologically based therapies for other disordersassociated with the human microbiome?
Cholera, gonorrhea, and pneumonia are some of thediseases caused by pathogenic___________ . Harmfulstrains of E. coli can be transmitted to humans byconsumption of_________ , ________, or__________.
Which of the following statements is incorrect? a. Mucosal surfaces are better than skin surfaces at supporting colonization by commensal microorganisms. b. The skin provides a larger surface area than mucosal surfaces for commensal microorganisms. c. There are ten times as many bacteria residing in the intestinal tract than the number of cells in the human body. d. It is common for commensal bacteria to live in symbiosis with their human hosts. e. During gestation in mammals, a fetus does not have any commensal microorganisms on their skin or mucosal surfaces.
Clostridium difficile is a part of the normal intentinal microbiota. When multiple antibiotics are used to treat infections, C. difficile can overgrow and cause mild to life threatening symptoms. So C, difficile is considered? A virulent pathogen a hereditary pathogen resident pathogen opportunistic pathogen primary pathogen
List the main features of Koch’s postulates and explain why it is sodifficult to prove them for some diseases.
Haemophilus influenzae is ________and requires special ____________for growth.a. motile, temperatures b. encapsulated, minerals c. intracellular, sample swabs d. fastidious, blood factors