is it understandable that antibiotics taken for a sore throat might cause intestinal discomfort?

Human Heredity: Principles and Issues (MindTap Course List)
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Chapter11: Genome Alterations: Mutation And Epigenetics
Section11.4: Mutations Can Be Spontaneous Or Induced
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Human beings carry a diverse community of bacterial species in their large intestine, including Escherichia coli strains that rarely cause disease in healthy people. The normal bacterial flora outcompetesany foreign bacterial species passing through the system. Based on these facts, is it understandable that antibiotics taken for a sore throat might cause intestinal discomfort?

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