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Compare and contrast fatty acid biosynthesis and -oxidation.

Compare and contrast fatty acid biosynthesis and -oxidation.

Biochemistry
Biochemistry
6th Edition
ISBN:9781305577206
Author:Reginald H. Garrett, Charles M. Grisham
Publisher:Reginald H. Garrett, Charles M. Grisham
Chapter18: Glycolysis
Section: Chapter Questions
Problem 24P: Based on your knowledge of the structure of NAD+ and an assumption that coenzyme dissociation is the...
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The second law of thermodynamics tells us that life evolved in a universe that tends towards disorder. Gases expand to fill the space enclosing them, dissolved molecules spread throughout the solvent containing them, and large molecules fall apart to become smaller ones. Despite this, we know that cells can make large molecules and break them down. Because of the first law of thermodynamics, (energy can't be created or destroyed, but it can be converted between forms) cells can carry out anabolism and catabolism. For example, they can make and breakdown fatty acids. In this question you will consider the strategies cells and enzymes used to perform these processes in the context of biosynthesis and oxidation of fatty acids.

Compare and contrast fatty acid biosynthesis and -oxidation.

Compare and contrast fatty acid biosynthesis and ß-oxidation. fatty acid biosynthesis (16.2) Add more rows as needed B-oxidation (16.1) Some questions to think about in your comparison. a) What reactions that either use or generate high energy metabolites? Consider those molecules in their high energy or their low energy forms. b) How is chemical energy exchanged using energy carriers (e.g. NAD+ has a stable aromatic ring while NADH does not). c) Consider water. Water isn't a high energy intermediate, but when there's a lot of it used or formed in a biochemical process, the entropy associated with water order/disorder can be important. d) Note steps or enzymatic reactions that are regulated and consider the importance of this regulation in preventing the waste that would occur if synthesis and breakdown occur simultaneously. e) How is compartmentalization exploited by the cell in fat metabolism?
Transcribed Image Text:Compare and contrast fatty acid biosynthesis and ß-oxidation. fatty acid biosynthesis (16.2) Add more rows as needed B-oxidation (16.1) Some questions to think about in your comparison. a) What reactions that either use or generate high energy metabolites? Consider those molecules in their high energy or their low energy forms. b) How is chemical energy exchanged using energy carriers (e.g. NAD+ has a stable aromatic ring while NADH does not). c) Consider water. Water isn't a high energy intermediate, but when there's a lot of it used or formed in a biochemical process, the entropy associated with water order/disorder can be important. d) Note steps or enzymatic reactions that are regulated and consider the importance of this regulation in preventing the waste that would occur if synthesis and breakdown occur simultaneously. e) How is compartmentalization exploited by the cell in fat metabolism?
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