Consider the data in the following table, derived from crossing a female fruit fly that was heterozygous for the sex-linked recessive loci, cut wings (ct), raspberry eyes (ra), and forked (f) bristles, with a wild-type male. Female progeny were all wild- type. Male progeny are listed below. Phenotype ct ra f + ra f + + + + ct + f ra + ct ra + Number of males 70 76 74 356 345 3
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- Hemophilia and color blindness are both recessive conditions caused by genes on the X chromosome. To calculate the recombination frequency between the two genes, you draw a large number of pedigrees that include grandfathers with both hemophilia and color blindness, their daughters (who presumably have one chromosome with two normal alleles and one chromosome with two mutant alleles), and the daughters sons. Analyzing all the pedigrees together shows that 25 grandsons have both color blindness and hemophilia, 24 have neither of the traits, 1 has color blindness only, and 1 has hemophilia only. How many centimorgans (map units) separate the hemophilia locus from the locus for color blindness?Three autosomal recessive mutations in yeast, all producing the same phenotype (m1, m2, and m3), are subjected to complementation analysis. Of the results shown below, which, if any, are alleles of one another? Predict the results of the cross that is not shown—that is, m2 * m3. Cross 1: m1 * m24 F1: all wild-type progeny Cross 2: m1 * m34 F1: all mutant progenyIn Drosophila fruit flies, the genes for warped wings (dwp), rumpled bristles (rmp), and pallid wings (pld) are linked. A trihybrid female for all three allleles is crossed with homozygous recessive male for all three alleles and the offspring obtained showed the following phenotypes: 3 pld rmp dwp 428 pld rmp + 427 + + dwp 48 + rmp + 47 pld + dwp 23 pld + + 2 + + + 22 + rmp dwp What is the order and map distance between these three alleles?
- A cross in Drosophila melanogaster involved the recessive X-linked genes for white eye (w), yellow body (y), and cut wings (c). A wild-type tri-hybrid female was crossed with wild-type males and only the male offspring were tallied. On the basis of the results shown below, which of the choices shown best represents the genetic map of the three loci on the X-chromosome? Phenotype Male Offspring + y ct 494 w + + 394 + + ct 28 w y + 35 + y + 105 w + ct 101 w y ct 5 + + + 3The following is a linkage map of chromosome 5 for three genes in tomato: (see image) The cross between the triple heterozygote (Lf J W/ lf j w) and a triple homozygous recessive produced 500 progeny. Assume that there is no interference in the Lf-W region. Give the expected number of individuals for each of the following progeny types and show complete solutions.a. with crossover in the Lf-J and J-W regionsb. with crossover in the Lf-J regionc. with crossover in the J-W regiond. without crossover in the Lf-W regionA cross was performed using Drosophila melanogaster involving a female known to be heterozygous for both ebony body and sepia eyes and a male known to be homozygous for both of these recessive traits. The following data was produced from the cross. Test these data to determine if they are significantly different from the expected phenotypic ratio. Remember to use the 5% level of significance Wild eye Wild body – 102, Wild eye Ebony body – 94, Sepia eye Wild body – 100, Sepia eye Ebony body – 93. Your answer should include the hypothesized cross in genotypes, the Chi-squared value, the critical value and whether you reject or do not reject.
- A homozygous strain of corn that produces yellow kernels is crossed with another homozygous strain that produces purple kernels. When the F1 are interbred, 197 of the F2 are yellow and 153 are prurple. Give the genotypes of the yellow and purple F2 and propose a genetic model that explains the inheritance of these kernel colors in corn.In a diploid plant species, an F1 with the genotype Mm Rr Ss is test crossed to a pure breeding recessive plant with the genotype mm rr ss. The offspring genotypes are as follows: Genotype Number Mm Rr Ss 687 Mm Rr ss 5 Mm rr Ss 68 Mm rr ss 196 mm Rr Ss 185 mm Rr ss 72 mm rr Ss 8 mm rr ss 679 Total 1900 1. What is the gene order of these linked genes?In Drosophila, the genes A, B, and C are linked and in the order given. The distances are A-B = 5 m.u. and B-C = 15 m.u. The interval exhibits 20% interference. How many double crossovers would be observed in a three-point cross involving A, B, and C out of 500 progeny?
- Two genes on chromosome 7 of corn are glossy (g) for leaf texture and ramosa (r), which determines how the ears branch. A test cross between a heterozygous plant for both loci and a doubly recessive plant produces the following progeny and genotypes Phenotype Number of corn kernels counted GR / gr 46 G r / gr 125 g r / gr 45 g R / gr 121 What is the recombination frequency (in %) for the two loci? ___Three recessive mutations in Drosophila melanogaster, roughoid (ru, small rough eyes), javelin (jv, cylindrical bristles), and sepia eyes (se, dark brown eyes) are linked. A three-point cross was carried out and the following progeny obtained: jv+ ru+ se+ 37 jv+ ru+ se 2 jv+ ru se 14 jv+ ru se+ 146 jv ru se+ 2 jv ru se 35 jv ru+ se 154 jv ru+ se+ 10 a. Determine the order of the genes on the chromosome. b. Determine which progeny contain single crossovers and which contain double crossovers and indicate where among the genes the crossovers occurred. c. Calculate the map distances among the genes. d. Calculate the coefficient of coincidence and interference among the genesTwo different female Drosophila were isolated, each heterozygous for the autosomally linked genes black body (b), dachs tarsus (d), and curved wings (c). These genes are in the order d–b–c, with b closer to d than to c. Shown in the following table is the genotypic arrangement for each female, along with the various gametes formed by both. Identify which categories are noncrossovers (NCO), single crossovers (SCO), and double crossovers (DCO) in each case. Then, indicate the relative frequency with which each will be produced.