Cystic fibrosis in humans is caused by mutations in a single gene and is inherited as an autosomal (non-sex chromosome) recessive trait. A normal couple has two children. The first child has cystic fibrosis, and the second child is unaffected. What is the probability that the second child is a carrier (heterozygous) for the mutation that causes the disease? 2/3 1/4 1/2 3/4
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- Chands syndrome is an autosomal recessive condition characterized by very curly hair, underdeveloped nails, and abnormally shaped eyelids. In the pedigree below: Which individuals must be carriers (heterozygotes)? ----- Imagine that you are a genetic counselor, and a couple planning to start a family comes to you for information. Charles wasmarried once before, and he and his first wife had a child withcystic fibrosis. The brother of his current wife, Elaine, died ofcystic fibrosis. What is the probability that Charles and Elainewill have a baby with cystic fibrosis? (Neither Charles, Elaine,nor their parents have cystic fibrosis.)The following Pedigree shows an unknown genetic disorder. The disorder is believed to be caused by single gene mutations. For the following disorder, determine whether the mutant gene is located on an autosome or X chromosome. 
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