Describe infection by Clostridium tetani and the effects oftetanus toxin. How does the mode of action of tetanus toxindiffer from that of alpha toxin produced by C. perfringens?

Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
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Describe infection by Clostridium tetani and the effects of
tetanus toxin. How does the mode of action of tetanus toxin
differ from that of alpha toxin produced by C. perfringens?

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Step 1

C. tetani is a rod-shaped, gram positive, endospore forming bacteria which have rotary flagellum in the peritrichous orientation. C. tetani strains are heat sensitive and cannot survive in the presence of oxygen. However, its spores are resistant to heat and some antiseptics. C. tetani is found mostly in warm, damp areas, especially in soil. These strains are also found in the intestines or faeces of many animals.

 

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