Describe the given synthetic pathway. Discuss type of reactions involved, the purpose of each reagent, and the relevance of each step. Provide brief explanation.

Chemistry
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ISBN:9781305957404
Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
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Chapter1: Chemical Foundations
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Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...
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  1. Describe the given synthetic pathway. Discuss type of reactions involved, the purpose of each reagent, and the relevance of each step. Provide brief explanation.
  2. Create a retrosynthetic map for the synthetic pathway in Question 1.
H,N.
urea, NaOH
n-butanol
reflux, 20h
reflux, 12h
Br
Brz, Fe, 80°C
1.5h
DMEDA, Cul,
K,COg, dioxane
100°C, 20h
N„H, H,O, FeCl,
MeOH, reflux, 6-8h
THF, Et,N, 0°C, 3h
reflux
HN
NH2
3h
но.
SOC, DCM
N.
reflux, 5h
но
HN
IZ
Transcribed Image Text:H,N. urea, NaOH n-butanol reflux, 20h reflux, 12h Br Brz, Fe, 80°C 1.5h DMEDA, Cul, K,COg, dioxane 100°C, 20h N„H, H,O, FeCl, MeOH, reflux, 6-8h THF, Et,N, 0°C, 3h reflux HN NH2 3h но. SOC, DCM N. reflux, 5h но HN IZ
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