Describe the substitution process for the reaction of Cisplatin and the guanine nucleobase with a focus on what is happening at the metal center and demonstrate your understanding of the kinetic factors involved. b) What advantages or disadvantages for the anticancer drug properties would result from using a Cisplatin-analog that has a faster rate of ligand substitution?
Describe the substitution process for the reaction of Cisplatin and the guanine nucleobase with a focus on what is happening at the metal center and demonstrate your understanding of the kinetic factors involved. b) What advantages or disadvantages for the anticancer drug properties would result from using a Cisplatin-analog that has a faster rate of ligand substitution?
Chapter12: Spectrochemical Methods
Section: Chapter Questions
Problem 13P
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) Describe the substitution process for the reaction of Cisplatin and the guanine nucleobase with a focus on what is happening at the metal center and demonstrate your understanding of the kinetic factors involved. b) What advantages or disadvantages for the anticancer drug properties would result from using a Cisplatin-analog that has a faster rate of ligand substitution?
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