Discuss: (a) the molecules and steps involved in the ACTH signal transduction pathway; (b) how the signal is amplified at its target cell; and (c) how the ACTH signal transduction pathway differs from the cortisol signal transduction pathway.
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- Match the endocrine control concepts.Which of these endocrine cells are also target cells for other hormones? (choose the most inclusive answer) adrenal cortex endocrine cells adrenal cortex endocrine cells and thyroid endocrine cells adrenal cortex endocrine cells, thyroid endocrine cells, and anterior pituitary endocrine cells none of the above endocrine cells are target cells for other hormonesIdentify a true statement about the pituitary gland. Multiple Choice The pituitary gland produces oxytocin and vasopressin. The posterior lobe of the pituitary synthesizes hormones. The posterior lobe of the pituitary gland is an extension of the nerve tissue of the hypothalamus. The hypothalamus produces the hormones that are stored in the anterior lobe of the pituitary gland.
- Which two of the following statements are correct? 1. for all cortisol assays, the corticosteroid-binding protein is also being measured 2. salivary cortisol represents 'free' 'active' cortisol 3. urinary cortisol contains bound and free cortisol 4. protein bound cortisol cannot enter cells 5. salivary cortisol contains bound and free cortisolIndicate whether the following statements about the pituitary glands are TRUE or FALSE. If the statement is false, correct the statement to make it true 1. The anterior and posterior pituitary glands are responsible for producing and releasing hormones. 2. The posterior pituitary gland is regulated by the hypothalamus via a positive feedback loop. 3. The hypothalamus regulates the release of cortisol via the sympathetic nervous system and that of epinephrine via the parasympathetic nervous system. 4. The releasing hormones from the hypothalamus stimulate the production of stimulating hormones and human growth hormone.List the statements that describe the endocrine system. Travels by blood Fast-acting Long-lasting effects Slow acting Short term effects Record your answers in ascending (lowest to highest) order.
- What data would indicate a positive clinical response after administration of corticosteroid hormones prescribed for the treatment of Addison’s disease?A 19-year-old with glucocorticoid resistance due to mutations in the glucocorticoid receptor in the ligand binding domain that markedly decreases the affinity of the receptor for cortisol. Which of the following findings is most likely? Decreased serum ACTH concentration Decreased serum sodium concentration Increased sensitivity to dexamethasone Increased serum cortisol concentration Increased serum glucose concentrationWhat are the primary target organs/tissues of cortisol? Describe the effect on each.
- Which of the following endocrine side effects is not typically seen with glucocorticoid use?A. Development of Cushing syndromeB. Increased virility in male patientsC. Delayed growth and development of pediatric patientsD. Decreased carbohydrate toleranceE. Disturbances in ovulatory/menstrual cyclesThe pituitary gland is often referred to as the master gland. Set aside the fact that this term is sexist and hegemonic. Instead, consider this definition from the Merriam Webster dictionary “being a device or mechanism that controls the operation of another mechanism.” Using examples from the anterior and posterior pituitary, explain how this definition could be appropriate Please answer asap and in short and content should not be palgarised please answer asapWhich of the followings best describe hypothalamic-pituitary-adrenal axis?A. Glucocorticoids are secreted by the adrenal cortex zona fasciculata B. Glucocorticoids exert effects on target tissues and also provide negative feedback to the anterior pituitary C. ACTH from the anterior pituitary exerts negative feedback on the hypothalamusD. All of the above are correctE. None of the above are correct