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- 2. How many substitution product/s is/are formed when metabromo anisole is treated with ammonia?A. 0-no reactionB. 1C. 2D. 3What is the expected major product of the reaction? 1. A 2. B 3. C 4. No reactionWhich of the following reacts the fastest with NaOH, H2O? A. cis-2,3-dimethyloxirane B. ethylene oxide (oxirane) C. trans-2,3-dimethyloxirane D. 2,2,3,3-tetramethyloxirane