Answered: Draw the mechanism for the following…

Draw the mechanism for the following reaction and account for the relative stereochemistry. MeO₂C MeO₂C CO₂Me Pd2(dba)3.CHCI 3 Ph3P, ACOH MeO₂C

EBK A SMALL SCALE APPROACH TO ORGANIC L

4th Edition

ISBN:9781305446021

Author:Lampman

Publisher:Lampman

Chapter35: Sonogashira Coupling Of Iodosubstituted Aromatic Compounds With Alkynes Using A Palladium Catalyst

Section: Chapter Questions

Problem 3Q

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Question

Draw the mechanism for the following reaction and account for the relative stereochemistry.
MeO₂C
MeO₂C CO₂Me
Pd2(dba)3.CHCI 3
Ph3P, ACOH
MeO₂C

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