Draw the mechanism for the synthesis of the phenyl magnesium bromide (Grignard reagent used in lab 3) starting with magnesium and bromobenzene
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Draw the mechanism for the synthesis of the phenyl magnesium bromide (Grignard reagent used in lab 3) starting with magnesium and bromobenzene
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- In the experiment, potassium permanganate is used to oxidize 2-chlorotoluene (o-chlorotoluene) to 2-chlorobenzoic acid (o-chlorobenzoic acid). Draw the step by step mechanism.What functional group cannot be present on the substrate when treating it with either an alkyllithium or Grignard reagent?Design a stepwise synthesis to convert cyclopentanone and 4- bromobutanal to hydroxy aldehyde A.
- Provide a synthetic route for the following compound using the indicated starting materialExplain why a Lewis acid is necessary in this aldol reaction. Include a structure formed by the Lewis Acid and one of the reactants that is key to your discussion. R group is p-methoxyphenyl to make p-methoxybenzaldehyde (reactant). R' is phenyl.Draw the product that results from this nucleophilic acyl substitution reaction.