During exercise when the body lacks an adequate supply of oxygen to support energy production, the pyruvate that is produced from the breakdown of glucose is converted into lactate. High lactate levels can lead to acidity in the muscle cells as some of the lactate hydrolyzes to lactic acid. The dissociation of lactic acid to lactate is shown in the reaction. Lactic acid has a pK, of 3.86. OH OH OH Lactic acid Lactate A solution containing a mixture of lactic acid and lactate was found to have a pH of 4.01. Calculate the ratio of the lactate concentration to the lactic acid concentration in this solution. [lactate] [lactic acid] * TOOLS x10

Organic Chemistry
9th Edition
ISBN:9781305080485
Author:John E. McMurry
Publisher:John E. McMurry
Chapter20: Carboxylic Acids And Nitriles
Section20.4: Substituent Effects On Acidity
Problem 7P: Dicarboxylic acids have two dissociation constants, one for the initial dissociation into a...
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During exercise when the body lacks an adequate supply of oxygen to support energy production, the pyruvate that is produced
from the breakdown of glucose is converted into lactate. High lactate levels can lead to acidity in the muscle cells as some of the
lactate hydrolyzes to lactic acid.
The dissociation of lactic acid to lactate is shown in the reaction. Lactic acid has a pKa of 3.86.
+ H*
OH
OH
OH
Lactic acid
Lactate
A solution containing a mixture of lactic acid and lactate was found to have a pH of 4.01. Calculate the ratio of the lactate
concentration to the lactic acid concentration in this solution.
[lactate]
[lactic acid]
* TOOLS
x10
Transcribed Image Text:During exercise when the body lacks an adequate supply of oxygen to support energy production, the pyruvate that is produced from the breakdown of glucose is converted into lactate. High lactate levels can lead to acidity in the muscle cells as some of the lactate hydrolyzes to lactic acid. The dissociation of lactic acid to lactate is shown in the reaction. Lactic acid has a pKa of 3.86. + H* OH OH OH Lactic acid Lactate A solution containing a mixture of lactic acid and lactate was found to have a pH of 4.01. Calculate the ratio of the lactate concentration to the lactic acid concentration in this solution. [lactate] [lactic acid] * TOOLS x10
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