During one of the genetics lab, you notice a few Drosophila fruit fly that has a rainbow body.  You transfer the rainbow bodied flies into a separate vial. That vial of rainbow-bodied flies is left  untouched for several months. As all flies in the vial continue to be rainbow-bodied, you assume they  are true breeding (homozygous). You want to determine the mode of inheritance of rainbow body flies  so set up crosses using wild type flies. You finally get the cross results, and they are as follow: F1 result Wild-type Mutant P: Wild-type female X Mutant male 0    258 P: Wild-type male X Mutant female 0    193 F2 result Wild-type Mutant F1 male x F1 female 268   205 a) Based on the proportions, what is the most likely mode of inheritance? b) You need to perform a statistical test to confirm the mode of inheritance. State the null hypothesis. c) What is the Chi-square value for F2? Show your calculations d) What conclusion can you make from these results?

Human Biology (MindTap Course List)
11th Edition
ISBN:9781305112100
Author:Cecie Starr, Beverly McMillan
Publisher:Cecie Starr, Beverly McMillan
Chapter20: Chromosomes And Human Genetics
Section: Chapter Questions
Problem 7CT: The following pedigree shows the pattern of inheritance of red-green color blindness in a family....
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 During one of the genetics lab, you notice a few Drosophila fruit fly that has a rainbow body. 
You transfer the rainbow bodied flies into a separate vial. That vial of rainbow-bodied flies is left 
untouched for several months. As all flies in the vial continue to be rainbow-bodied, you assume they 
are true breeding (homozygous). You want to determine the mode of inheritance of rainbow body flies 
so set up crosses using wild type flies. You finally get the cross results, and they are as follow:
F1 result Wild-type Mutant
P: Wild-type female X Mutant male 0    258
P: Wild-type male X Mutant female 0    193
F2 result Wild-type Mutant
F1 male x F1 female 268   205
a) Based on the proportions, what is the most likely mode of inheritance?
b) You need to perform a statistical test to confirm the mode of inheritance. State the null hypothesis.
c) What is the Chi-square value for F2? Show your calculations
d) What conclusion can you make from these results?

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