EXPERIMENT S1: PREPARATION OF ACETANILIDES Estimated time: one afternoon Pre-lab report: complete the standard report form, and answer the following questions. 1. Briefly outline the mechanism of the reaction.

Macroscale and Microscale Organic Experiments
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Author:Kenneth L. Williamson, Katherine M. Masters
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Chapter10: Gas Chromatography: Analyzing Alkene Isomers
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EXPERIMENT S1: PREPARATION OF ACETANILIDES
Estimated time: one afternoon
Pre-lab report: complete the standard report form, and answer the following questions.
1. Briefly outline the mechanism of the reaction.
In principle one can replace both hydrogen atoms of the aromatic amine with acetyl groups.
2.
Why is the N,N-bis(acetyl) product difficult to form?
On the basis of the mechanism you proposed in 1 above, predict the likely product formed from
succinic anhydride and two equivalents of your aromatic amine.
3.
Transcribed Image Text:EXPERIMENT S1: PREPARATION OF ACETANILIDES Estimated time: one afternoon Pre-lab report: complete the standard report form, and answer the following questions. 1. Briefly outline the mechanism of the reaction. In principle one can replace both hydrogen atoms of the aromatic amine with acetyl groups. 2. Why is the N,N-bis(acetyl) product difficult to form? On the basis of the mechanism you proposed in 1 above, predict the likely product formed from succinic anhydride and two equivalents of your aromatic amine. 3.
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