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Explain how bacterial infection can be associated with Neutrophilia and Neutropenia?

Explain how bacterial infection can be associated with Neutrophilia and Neutropenia?

Human Physiology: From Cells to Systems (MindTap Course List)
Human Physiology: From Cells to Systems (MindTap Course List)
9th Edition
ISBN:9781285866932
Author:Lauralee Sherwood
Publisher:Lauralee Sherwood
Chapter11: The Blood
Section: Chapter Questions
Problem 11RE
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Explain how bacterial infection can be associated with Neutrophilia and Neutropenia?
1.3 A 60-year-old woman with the history of rheumatoid arthritis, smoking 60 packs/y, chronic obstructive pulmonary disease and treated hypertension underwent a screening colonoscopy and the felt poorly for a week. She saw a physician, who referred to the local cinic where they did a list of blood tests as indicated below: Tests Results Ref ranges 3.7 mg/dl 35mg/dl 12.5 ml/min Creatinine Females <1.2 BUN 5-20 Creatinine Clearance 75-115 148mg/dl 19mg/dl 4.1 a/dl positive C3 80-200 C4 15-80 Albumin 3.5-5 Cryoglobulin screen Serum protein electrophoresis (SPE)- polyclonal hyperglobinemia with no monoclonalimmunoglobulin spike identified. Urine sediment: no RBC, 4-8WBC's/hpf, granular and hyaline casts 1.3.1 What disease state is the most likely explanation for the patients results. 1.3.2 What is the clinical significance of polydonal hypergammaglobunemia with no monoclonal spike identified on SPE. 1.3.3 What is the clinical significance of a positive Cryoglobulin screen. D Facus 0 25°C Sunn B N M
Transcribed Image Text:1.3 A 60-year-old woman with the history of rheumatoid arthritis, smoking 60 packs/y, chronic obstructive pulmonary disease and treated hypertension underwent a screening colonoscopy and the felt poorly for a week. She saw a physician, who referred to the local cinic where they did a list of blood tests as indicated below: Tests Results Ref ranges 3.7 mg/dl 35mg/dl 12.5 ml/min Creatinine Females <1.2 BUN 5-20 Creatinine Clearance 75-115 148mg/dl 19mg/dl 4.1 a/dl positive C3 80-200 C4 15-80 Albumin 3.5-5 Cryoglobulin screen Serum protein electrophoresis (SPE)- polyclonal hyperglobinemia with no monoclonalimmunoglobulin spike identified. Urine sediment: no RBC, 4-8WBC's/hpf, granular and hyaline casts 1.3.1 What disease state is the most likely explanation for the patients results. 1.3.2 What is the clinical significance of polydonal hypergammaglobunemia with no monoclonal spike identified on SPE. 1.3.3 What is the clinical significance of a positive Cryoglobulin screen. D Facus 0 25°C Sunn B N M
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