Explain the Titrimetric profile of Lysine in figure 2

An Illustrated Guide To Vet Med Term
4th Edition
ISBN:9781305465763
Author:ROMICH
Publisher:ROMICH
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Explain the Titrimetric profile of Lysine in figure 2.
pka values that surround the zwitterion
Zwitterion
H.
H3N*-Ć -COOH
H3N* -C-CO"
H2N–C- C0-
H2N-C-CO-
pka,=8.95
pka;=2.18
CH2
CH2
CH2
CH2
CH2
CH2
CH2
CH2
pH = 2.18
pH = 8.95
pH = 10.79
CH2
CH2
CH2
CH2
CH2
CH2
CH2
CH2
NH3+
NH3*
NH3*
NH2
pKa=10.79
Net charge:
+2
+1
- 1
8.95+10.79
Isoelectric pH (pl) =
= 9.87
Figure 2. Titrimetric profile of Lysine using theoretical pKa values
Transcribed Image Text:pka values that surround the zwitterion Zwitterion H. H3N*-Ć -COOH H3N* -C-CO" H2N–C- C0- H2N-C-CO- pka,=8.95 pka;=2.18 CH2 CH2 CH2 CH2 CH2 CH2 CH2 CH2 pH = 2.18 pH = 8.95 pH = 10.79 CH2 CH2 CH2 CH2 CH2 CH2 CH2 CH2 NH3+ NH3* NH3* NH2 pKa=10.79 Net charge: +2 +1 - 1 8.95+10.79 Isoelectric pH (pl) = = 9.87 Figure 2. Titrimetric profile of Lysine using theoretical pKa values
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