Q: what possible outcome may be produced when the molecular weight of an alcohol antiseptic is increase…
A: Alcohol-based treatments are one of the easiest and widely used methods of preventing nosocomial…
Q: What are the differences between synthesis of phosphatidylethanolamine in prokaryotes and…
A: Glycerol is a polyol compound that is made up of more than one hydroxyl group. Glycerol is a…
Q: draw a peptide bond of: glycine alanine proline
A: The amino acids are the monomers for the protein chains. The amino acid has a chiral carbon attach…
Q: Transition-state analogs, which can be used as enzyme inhibitors and to generate catalytic…
A: Compounds resembling the transition state of a catalyzed reaction should be very effective…
Q: What are statins? What is their pharmacological function?
A: Cholesterol plays a role in normal cell and boock bdy function. However, very high levels can lead…
Q: A sample of an unknown peptide was divided into two aliquots. One aliquot was treated with trypsin,…
A: Proteolytic cleavage is basically the process of breaking the peptide bonds between amino acids in…
Q: Peptide YY (PYY) is a 36-amino acid peptide that is so named because it contains twobiochemically…
A: Peptide YY (PYY) is 36-amino-acid peptide and contains two biochemically relevant tyrosine residues
Q: Sodium nitrite, a common food preservative (page 906), is capable of causing mutations in an acidic…
A: Sodium nitrite, a common food preservative , is capable of causing mutations in an acidic…
Q: What are the possible sources of errors or deviations between the theoretical and experimental pKa…
A: pKa value: pKa or Acid dissociation constant is also known as acidity constant or acid-ionization…
Q: the key features between glycosaminoglycan-binding proteins and lectins?
A: Glycosaminoglycans (GAGs) are mucopolysaccharides containing a large number of disaccharide units…
Q: Similarly, hypoxanthine (HX) can be used to label purine residues. As in Problem 4, write reactions…
A: It is given that hypoxanthine can be used to label the purine residues. Hypoxanthine always pair…
Q: The purine and pyrimidine rings are built from the amino acids aspartate,glutamine, and glycine. Why…
A: A deoxyribonucleotide is a nucleotide that contains deoxyribose. They are the monomeric units of the…
Q: What function does a guanine nucleotide exchange factor(GEF) serve?
A: Small GTPases or small G-protein is a type of hydrolase enzyme found in the cytosol of the cell.…
Q: Draw the dipeptide alanylvaline
A: Introduction Amino acids are organic compounds that contain the functional groups amino (–NH2) and…
Q: Determine the codon sequence for the peptide sequence glycylserylcysteinylarginylalanine. How many…
A: Translation is the sequences process where the mRNA was translated into a polypeptide chain. Where…
Q: In the serine protease triad, the proximity of an aspartatecarboxylate group to the imidazole group…
A: A serine protease triad is referred to as the protease that catalyzes the hydrolysis of the peptide…
Q: Explain why cleavage of the bond between arginine 15 and isoleucine 16 of chymotrypsinogen activates…
A: Enzymes are known as biological catalysts in which help to catalyze the different biochemical…
Q: A drug company has decided to use recombinant DNA methods to prepare a modified α1 -antitrypsin that…
A: Amino acids are the organic compounds join to form proteins.
Q: Tyrosine is a nonessential amino acid in humans. Under what circumstance would it become an…
A: Amino acids are biomolecules serving as the building blocks of proteins. These have a carboxylic…
Q: Which of the sequences of Pharmacokinetic Phase does Morphine sulfate follow in terms of its drug…
A: MORPHINE SULFATE:- A drug that is used to treat moderate to severe pain. It binds to opioid…
Q: Why is trypsin an unusual name for an enzyme? (What is the convention for enzyme names?) .
A: The enzymes are the biocatalyst that perform specific biochemical reaction within the body and after…
Q: you were given an unknown peptide. Explain in detail how you would determine the amino acid sequence…
A: The amino acids that form the protein are mostly L forms. The carboxyl group of amino acids in the…
Q: what is the mainstream solid phase peptide synthesis ( with detailed mechanisms and intermediates )…
A: Lysine reactive probes are attractive alternatives to cysteine reactive probes when there is no…
Q: What is the purpose of dideoxyribonucleoside triphosphates, or ddNTPs?
A: DdNTPs are called as dideoxynucleotides triphosphates. It includes 4 types of nucleotides i.e…
Q: A pyrimidinr always pairs with a ___________
A:
Q: Why do both thymine and uracil specify the incorporation of adenine?
A:
Q: Briefly discuss the synthesis of selenocysteine amino acid.
A: Selenocysteine(Sec): It is the 21 st amino acid of the genetic code and this amino acid contains…
Q: Acid hydrolysis of polypeptides may lead to complete destruction of tyrosine residues.
A: Proteins and peptides are macromolecules made up of covalently bonded amino acid residues in linear…
Q: In the serine protease triad, the proximity of an aspartate carboxylate group of histidine raises…
A: Serine protease is a class of proteolytic enzymes in which serine residue is present at the active…
Q: What is the Rf value of each amino acid observed?
A: Rf ( retardation factor):- It is defined as the ratio of distance traveled by the centre of a spot (…
Q: _____________ are degrons with sequences containing proline, glutamate, serine, and threonine…
A: Peptides are chain of amino acids containing few amino acids. The amino acids are attached with…
Q: A patient is suffering from hemoglobinopathies and the principal biochemical defect that leads to…
A: Haemoglobinopathies is a blood disorder.
Q: Write a DNA sequence that would encode the amino acid sequence…
A: In DNA, the hereditary information is contained within the nucleotides called codons that correspond…
Q: 5-Bromouracil is an analogue of thymine that usually pairswith adenine. However, 5-bromouracil…
A: Introduction 5-Bromouracil, a base analogue of thymine is a well-known mutagen that causes…
Q: What is the biochemical information you acquire from amino acid sequence? Give three examples.
A: A polypeptide is composed of a long chain of amino acids, which are joined through peptide bonds by…
Q: In a paragraph form, provide the experimental procedures in removal of the carbon dioxide present in…
A: Proteins are composed of amino acids in which amine group of one amino acid linked to carboxyl group…
Q: What aminos acid would the anticodon GAC be translated into?
A: * DNA will have four nucleotides Adenine Guanine Cytosine Thymine * RNA will have four…
Q: Explain the biochemical defect that leads to Lesch-Nyhan syndrome and suggest how the defect might…
A: Introduction: Purines (adenine and guanine) and pyrimidines (cytosine, thymine, and uracil) play…
Q: what are the necessary conditions for the okazaki fragments
A: Nucleic acid synthesis occurs solely within the 5'->3' direction as a result of the…
Q: Bisphosphoglycerate lies in a central cavity within the hemoglobin tetramer, stabilizing the T…
A: Hemoglobin (Hb) is the protein complex, which is a tetramer in a structure that binds to the oxygen…
Q: Glutamate, a 5-carbon amino acid, is the precursor of three other amino acids that contain a…
A: Glutamate is a negatively charged R group amino acid that is hydrophilic in nature where the R -…
Q: A drug company has decided to use recombinant DNA methods to prepare a modified α 1 - antitrypsin…
A: When a drug company is using recombinant DNA method to prepare a modified antitrypsin that is more…
Q: Similarly, hypoxanthine (HX) can be used to label purine residues. As in Problem 4, write reactions…
A: It is given that hypoxanthine can be used to label the purine residues. Hypoxanthine always pair…
Q: Why are structural analogs of sugar molecules (such as Oseltamivir and zanamivir) effective in…
A: The major surface glycoproteins used by the influenza virus in order to cause infections are…
Q: What do carboxypeptidase andaminopeptidase have in common? Identify asmany differences between them…
A: Aminopeptidase and carboxypeptidase are the protease class of enzymes. Proteases hydrolyze the…
Q: What intermediate in purine synthesis will accumulate if a strain of bacteria is lacking each of the…
A: The pathways for the biosynthesis of nucleotides fall into two classes: de novo pathways and salvage…
Discuss the Pharmacokinetics of morphine sulfate using the correct sequence you have chosen in question number one.
Step by step
Solved in 2 steps
- In a paragraph form, provide the experimental procedures in removal of the carbon dioxide present in the mechanism of reaction of protein that contain native serine residues by the reaction of oxazetidine-containing peptides and α-ketoacidWhat are the medical/ therapeutic applications of the nucleotide sleectivity?Draw the structure of the PTH derivative product you would obtain by Edman degradation of the following peptides: (a) I-L-P-F (b) D-T-S-G-A
- What aminos acid would the anticodon GAC be translated into? Please explain how you went about getting to the answer to the question.Draw the structure of the PTH derivative you would obtain by Edman degredation of the peptide: ALPF.A drug company has decided to use recombinant DNA methods to prepare a modified α1 -antitrypsin that will be more resistant to oxidation than is the naturally occurring inhibitor. Which single amino acid substitution would you recommend?
- A drug company has decided to use recombinant DNA methods to prepare a modified α 1 - antitrypsin that will be more resistant to oxidation than is the naturally occurring inhibitor. Which single amino acid substitution would you recommend?Name the following biomolecules. In the case of peptides, alos provide 3 - letter codes.For the conversion of Trypsinogen into Trypsin, how many amino acids should be cleaved and from which site? Write down the sequence of these amino acids.
- Draw all the possible tripeptides of serine, methionine, and glycine and name them.A pyrimidinr always pairs with a ___________Under certain conditions, peptide bond formation is more thermodynamically favorable than peptide bond hydrolysis. Would you expect chymotrypsin to catalyze peptide bond formation?