Answered: Explain the typical immunophenotypic…

Explain the typical immunophenotypic features of peripheral B cells in: (i) X-linked Agammaglobulinaemia (ii) CD40L (CD154) deficiency (iii) B-Chronic Lymphocytic Leukaemia. ww

Anatomy & Physiology

1st Edition

ISBN:9781938168130

Author:Kelly A. Young, James A. Wise, Peter DeSaix, Dean H. Kruse, Brandon Poe, Eddie Johnson, Jody E. Johnson, Oksana Korol, J. Gordon Betts, Mark Womble

Publisher:Kelly A. Young, James A. Wise, Peter DeSaix, Dean H. Kruse, Brandon Poe, Eddie Johnson, Jody E. Johnson, Oksana Korol, J. Gordon Betts, Mark Womble

Chapter21: The Lymphatic And Immune System

Section: Chapter Questions

Problem 44CTQ: Describe how secondary B cell responses are developed.

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Concept explainers

Immunology

Immunology is the division of science involved with the immune reactions occurring in living organisms. The organisms are accustomed to evolving internal defense mechanisms to evade the invasion of microbial pathogens. Diverse cells are connected with stimulating the immune responses, which produce inhospitable conditions to the microbes prompting their lysis and thus inhibits the multiplication of the pathogens. The immune system can distinguish the pathogens through the aid of cellular intercommunication and launch responses to destroy them.

Question

Explain the typical immunophenotypic features of peripheral B cells in:
(i)
X-linked Agammaglobulinaemia
(ii)
CD40L (CD154) deficiency
(iii)
B-Chronic Lymphocytic Leukaemia.
ww

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