Factors that could improve water solubility of drug molecules: * Presence of aromatic ring High degree of ionization Hydrogen bond-formation Exhibit dipole to dipole interaction

Q: Explain why a 1 ° amine and a 3 ° amine having the same number of carbons are soluble in water to a…

A: Primary and secondary amines have higher boiling points than those of alkanes or ethers of similar…

Q: What type of intermolecular attractive interaction exists in the pair of methanol and acetone?

A: The given pair of methanol and acetone are polar molecules.

Q: Rank the following compounds in order of increasing strength of intermolecular forces:…

A: The forces which provide interaction including force of repulsion and attraction acting between the…

Q: Draw two different possible hydrogen-bonding interactions between twomolecules of formamide…

A: Hydrogen bonds are the weaker bond than the covalent bond. These bonds are established between two…

Q: Look for the functional groups present in the following drug substance. Highlight the structure of…

A: The functional group in caffeine are : Amide , amine, alkene.

Q: Directions: Arrange these fatty acids (all contain 18 carbon atoms) in order of increasing melting…

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Q: Which of the attached molecules can hydrogen bond to another molecule like itself? Which can…

A: Since we only answer upto 3 sub-parts we'll answer first 3. Please resubmit the question and specify…

Q: EXPLAIN THE INTERACTION BETWEEN THE SOLUTE AND SOLVENT IN TERMS OF THEIR STRUCTURE.   1. Why is…

A: Ethanol is soluble in water because of the fact that it can form a hydrogen bond with the water…

Q: 12. Which substance would have the highest boiling point? a. Propane b. Propanol c. 1-Propanamine d.…

A: Since you have asked multiple questions, we will solve the first question for you. If you want any…

Q: Rank the following molecules in order of increasing strength of intermolecular forces.…

A: Strength of intermolecular forces depends on the interaction of groups or bonds in the system.

Q: Which of the following benzene derivatives would be most soluble in benzene? Why? Compound A…

A: Compund which is more soluble in benzene is given below.

Q: arrange the following compounds in order of increasing boiling point. Circle the mostwater soluble…

A: The boiling point depends on the strength of intermolecular forces. The more stronger the…

Q: How many hydrogen bonds can the following compound form with water? OH

A: Hydrogen atom is very less electronegative element. When it is bonded with more electronegative…

Q: Evaporation and Intermolecular Attractive Forces Complete the following data table. AT (°C) 10.47…

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Q: What is the relationship between strength of intermolecular forces and the rate of evaporation…

A: Methylated spirit is nothing but ethanol mixed with substances to make it unfit for consumption.

Q: H₂C. H₂C CH3 Compound 1 Compound 3 CH3 CH3 Apply your understanding of intermolcular forces to…

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Q: Using the given IUPAC name 4-chloro-3,4-dimethylnonan-1-amine Please help with the following:…

A: In chemistry, a molecule is called as chiral if it cannot be superimposed on its mirror image. This…

Q: Draw three methanol molecules showing their hydrogen-bonding interactions

A: Methanol molecules have molecular formula CH3OH

Q: Place the following molecules in order from lowest boiling point to highest boiling point, according…

A: Boiling point depends on molecular mass & intermolecular forces of interaction. Higher the…

Q: those that do hydrogen bond, draw a diagram of two molecules using a dotted line to indicate where…

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Q: What type(s) of intermolecular forces must be overcome when liquid dipropyl ether…

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Q: what intermolecular forces cause ethyl acetate to be insoluble in water, but soluble in hexane?

A: The rule is that : like dissolve like. The predominant intermolecular force present in ethyl acetate…

Q: What type(s) of intermolecular forces must be overcome when liquid hexanol (CH3CH2CH2CH2CH2CH2OH)…

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Q: How many hydrogen bonds form between methanol molecules? Draw this interaction.

A: Hydrogen bonding is the bond between hydrogen formed between hydrogen and most electronegative…

Q: what is a hydrogen bond? a,b,c or d a)a bond between two hydrogen atoms b)a strong bond between…

A: Hydrogen bond: a weak bond between two molecules resulting from an electrostatic attraction between…

Q: Draw two different possible hydrogen-bonding interactions between two molecules of formamide…

A: Hydrogen bonding interactions are the weaker bonds, which are present between two electronegative…

Q: Which of the following would be MOST soluble in water? CH3CH2CH2CH2CH2NH2 All of these would have…

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Q: How many hydrogen bonds can CH3NH2 make to water?

A: CH3NH2 can only have as many hydrogen bonds as hydrogen bonding sites in the molecule. CH3NH2 has…

Q: Quinapril (trade name Accupril) is a drug used to treat hypertension andcongestive heart failure.…

A: The site sites that can form hydrogen bond to acetone in quinapril can be shown as follows,

Q: What is the effect of dipole moment and intermolecular forces to the lipophilicity of hydrocarbons?…

A: lipophilicity of hydrocarbons : ability of any hydrocabons to dissolve in oil, fats, lipids and…

Q: Draw a picture of the hydrogen bonding in methanol.

A: Hydrogen bond is a force which produces a specific dipole-dipole interaction. A H-bond is produced…

Q: Which of the following situations will alcohol be at the lowest percentage? A. Equal amounts of…

A: Alcohol can be defined as an compound in which a hydroxyl group is bound to a carbon atom

Q: Select the molecules that can hydrogen bond with water Multiple answers: Multiple answers are…

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Q: (a) Which of the following molecules can hydrogen bond to another molecule like itself? (b) Which of…

A: a) The molecules which will have H attached to high electronegative elements like O, N, Cl, and F…

Q: What types of intermolecular forces do morphine and heroin each possess?

A: Intermolecular forces (IMF) are the forces of attraction or repulsion which exists between different…

Q: Explain why aldehydes are water soluble. SELECT all that applies. There may be multiple answers. O…

A: A compound becomes solubles in other solvent due to various reason .

Q: Choose from: A = intermolecular H-bonding B = London dispersion forces C = intramolecular…

A: 1. Benzene’s solubility in water is very low (0.08 g/100 mL) but that of toluene is even lower (0.06…

Q: List the following compounds in order of increasing boiling point: Increasing boiling point Drag and…

A: The given compounds are, butanoic acid, pentanal, 1-pentanol, 3-methylpentane.

Q: Propanone is very soluble in water because а. it is non-polar b. the dipole-dipole interactions are…

A: Propanone ( CH3COCH3 ) is a ketone , very soluble in water.  Ketones and aldehydes don't form…

Q: Explain briefly why esters are less soluble in water than carboxylic acids of comparable molecular…

A: The solubility of a compound follows the rule of like dissolves like. This means that polar…

Q: Draw a diagram to explain Hydrogen bonding between two ethanol molecules.

A: Hydrogen bonding is a special type of dipole - dipole interaction between molecules, not a covalent…

Q: Which organic solvent would be most soluble in water? Select one: O a. CH,CH, CH,CH,CH, CH, o b. CH,…

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Q: The compounds shown below are natural stimulant as chocolates, tea, and coffee beans. Which of the…

A: Xanthine, caffeine, theophylline and theobromine are natural stimulants used in chocolates, tea and…

Q: Using the given IUPAC name 4-chloro-3,4-dimethylnonan-1-amine Please help with the following:…

A: Hydrogen bond is primarily electrostatic force of attraction between a hydrogen atom which…

Q: Which of the following compounds cannot form hydrogen bonds with water? CH3-CH2-CH3 0 0 CH3C -O-CH3…

A: Each molecule of H2O has two hydrogen atoms and two oxygen atoms with two lone pairs of electrons.…

Q: Q8. Pentanoic acid has a very strong pungent smell and is generally used in perfumes after…

A: The question is based on the concept of physical properties. we have to identify the physical…

Q: 3. What kind of binding forces hold atoms together in anethanoic acid (CH3COOH) molecule? A Hydrogen…

A: CH3COOH) has the ability to hydrogen-bond. It will probably have the strongest intermolecular…

Q: Name and describe the intermolecular forces that are responsible for methylated spirits to dissolve…

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Q: Rank the attached compounds in order of increasing boiling point. Which compound is the most water…

A: All the given compounds have polar nature and they show dipole-dipole interactions.  The hydrogen…

Alkanes and Cycloalkanes

Alkanes are saturated organic compounds which are made up of C and H atoms. Alkanes have the general formula of CnH2n+2. Alkane contains sp3 hybridized carbon atoms with four sigmas (σ) bonds & every hydrogen atom is connected with one of the carbon atoms. The size of the alkane could be determined by the number of carbon atoms located in it.