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- Focus on the interaction of ATP with the kinase first. Would you say ATP binds on the surface of the kinase or in a cleft? What color are the phosphorus atoms? What color are the Mn2+ ions?Which part of ATP do the Mn2+ ions interact with?SNAT2 (a membrane protein) determines the cell’s content of most amino acids. It acts as a symport (or co-transporter) of Na+ and amino acids. On the outside of the cell, the Na+ concentration is higher than the inside. The amino acid concentration on the inside of the cell is higher than the outside. When both Na+ and an amino acid bind to the SNAT2 membrane channel on the outside of the cell, there is a conformational change allowing the energy from electrochemical gradient of Na+ for the transport of the amino acid into the cell. a. Draw this scenario and label your representations of Na+, amino acids, SNAT2, and the membrane. b. What kind of transport is this, simple diffusion, facilitated, diffusion, active transport, 1o active transport, or 2o active transport? Explain your choice. ThanksCalculate the membrane potential in the transport of Cl- from the intracellular environment to the extracellular environment. The Cl- concentration outside the cell is 98 uM, the Cl- concentration in the cytoplasm is 0.025 mM, the Gibbs free energy is -956 J/mol and the temp is 37°C. Have concentration in uM units when solving.
- Give 4 similarities and 4 differences between and nature and/or role of membrane potentials in a neuron and in a mitochondrion.Lactose transporter of E. coli is a well-studied proton driven cotransporter. It transports one lactose molecule together with one proton into the cell. Calculate the free energy change for transporting one more of protons into the cell? Membrane potential is -50 mV (inside is negative) and the pH = 7.2 inside the cell and the pH = 4.0 outside the cell. Temperature is 37 degrees celsius (310K). Remeber to convert pH to (H+) and express your answer as kJ/mol.HELPING TAGS: Biology, developmental biology, plants, actin filaments Can non-motile cells, such as plants, benefit from actin filaments' motion-related functions? Explain your answer. Will UPVOTE, just pls help me answer the question. Thanks.
- Exposing cells to which of the following drugs would inhibit the slow output response of a cell to a signaling ligandwithout having an effect on the fast output response ? A. Latrunculin - a molecule isolated from sponges, which binds near the nucleotide-binding cleft of monomericactin.B. Taxol - a molecule isolated from the bark of the pacific yew, which that stabilizes microtubules.C. Alpha-amanitin - a molecule isolated from deathcap mushrooms, which blocks RNA polymerase II.D. Phalloidin - a molecule isolated from deathcap mushrooms that stabilizes f-actin.E. Sodium orthovanadate - a molecule that inhibits alkaline and tyrosine phosphatases.Calculate the energy cost (free-energy change) of pumping Ca2+ from thecytosol, where its concentration is about 1.0 × 10−7 M, to the extracellularfluid, where its concentration is about 1.0 mM. Assume a temperature of 37°C (body temperature in a mammal) and a standard transmembrane potentialof 50 mV (inside negative) for the plasma membrane.true or false? And why it is false For the actin cytoskeleton, diverse cell-surface receptors trigger global structural rearrangements in response to external signals. But all these signals seem to converge inside the cell on a group of closely related monomeric GTPases that are members of the Rho protein family—Cdc42, Ras, and Rho. The same Rho family proteins are also involved in the establishment of many kinds of cell polarity.
- Steady state vs burst activity – why is aerobic better for steady state and anaerobic better for burstQuestion:- Regarding how information is passed through the cell, why is the state (confirmation) of a cell changed when other molecules are added or removed?Although purified actin can assemble reversibly in vitro, various actin-binding proteins regulate the assembly of actin filaments in the cell. Predict the effect on a cell’s actin cytoskeleton if function-blocking antibodies against each of the following were independently microinjected into cells: profilin, thymosin-β4, CapZ, and the Arp2/3 complex.