For a given acid HA, it was determined that at pH 6.0 the concentration of the conjugate base [A] was 0.075 M and the acid [HA] was 0.025 M. What percent of this acid is ionized at pH 6.0? What is the pKa of this acid? What pH would this acid be 50% ionized?

Organic Chemistry
9th Edition
ISBN:9781305080485
Author:John E. McMurry
Publisher:John E. McMurry
Chapter20: Carboxylic Acids And Nitriles
Section20.4: Substituent Effects On Acidity
Problem 7P: Dicarboxylic acids have two dissociation constants, one for the initial dissociation into a...
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For a given acid HA, it was determined that at pH 6.0 the concentration of the conjugate base [A]
was 0.075 M and the acid [HA] was 0.025 M.
What percent of this acid is ionized at pH 6.0?
What is the pKa of this acid?
What pH would this acid be 50% lonized?
Transcribed Image Text:For a given acid HA, it was determined that at pH 6.0 the concentration of the conjugate base [A] was 0.075 M and the acid [HA] was 0.025 M. What percent of this acid is ionized at pH 6.0? What is the pKa of this acid? What pH would this acid be 50% lonized?
Under anerobic conditions, when our bodies lack enough oxygen to complete respiration, the
product of the glycolytic pathway, pyruvate, is reduced to lactate in an effort to allow for energy
production to continue. Lactate is the conjugate base of lactic acid, thus high lactate levels can lead
to a drop in pH in our muscle cells.
0
OH
OH
0
C
сH, - с
C
CH, + H
HO
H
0
H
hydrogen
ion
lactic acid
lactate
The ionization of lactic acid to lactate has a K₂ of 1.585 x 10-4.
A solution containing a mixture of lactic acid and lactate was found to have a pH of 3.80.
What percent of that solution is lactate?
с
Transcribed Image Text:Under anerobic conditions, when our bodies lack enough oxygen to complete respiration, the product of the glycolytic pathway, pyruvate, is reduced to lactate in an effort to allow for energy production to continue. Lactate is the conjugate base of lactic acid, thus high lactate levels can lead to a drop in pH in our muscle cells. 0 OH OH 0 C сH, - с C CH, + H HO H 0 H hydrogen ion lactic acid lactate The ionization of lactic acid to lactate has a K₂ of 1.585 x 10-4. A solution containing a mixture of lactic acid and lactate was found to have a pH of 3.80. What percent of that solution is lactate? с
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