Answered: For each of the following, describe the…

Human Anatomy & Physiology (11th Edition)

11th Edition

ISBN:9780134580999

Author:Elaine N. Marieb, Katja N. Hoehn

Publisher:Elaine N. Marieb, Katja N. Hoehn

Chapter1: The Human Body: An Orientation

Section: Chapter Questions

Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...

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For each of the following, describe the path the protein takes to its final destination in the cell.
Drawings are strongly recommended!
Proteins: 1) Hedgehog (released from the signaling cell), 2) Smoothened, 3) Ci/GliYour answers should include the following if they apply for each protein:
o Sorting sequences and how the protein knows where to go at each step (what recognizes
different sorting sequences/tags)
o How/when the protein is inserted into the membrane (if it is a membrane protein)
o What organelles the protein passes through on its way to its final destination
o How the protein is transported (vesicles? translocons? etc.), including a role for microtubules
o How the protein might be modified in each organelle it passes through
o What other proteins are involved in transport and how the system is reset to allow for other
proteins to be transported

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