For the amino acid alanine, the major species in solution at pH 7 is the zwitterionic form, which has a negatively charged carboxylic acid group and a positively charged amino group. There is a less common neutral form in which neither group is charged. The carboxylic acid group of alanine has a p?a of 3 The amino group of alanine has a p?a of 8 Estimate the ratio of the concentration of the neutral amino acid species to the zwitterionic species at pH 7.   __?__x10^?

Chemistry: The Molecular Science
5th Edition
ISBN:9781285199047
Author:John W. Moore, Conrad L. Stanitski
Publisher:John W. Moore, Conrad L. Stanitski
Chapter14: Acids And Bases
Section14.6: Molecular Structure And Acid Strength
Problem 14.16CE
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For the amino acid alanine, the major species in solution at pH 7 is the zwitterionic form, which has a negatively charged carboxylic acid group and a positively charged amino group. There is a less common neutral form in which neither group is charged.

The carboxylic acid group of alanine has a p?a of 3 The amino group of alanine has a p?a of 8

Estimate the ratio of the concentration of the neutral amino acid species to the zwitterionic species at pH 7.

 

__?__x10^?

Expert Solution
Step 1

According to the given question,

pKa of carboxylic acid group of alanine is given by = 3  pKa of amino group of alanine is given by  = 8

 

Find - The ratio of the concentration of the neutral amino acid species to the zwitterionic species at pH 7

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