formation? thrombin; fibrinogen prothrombin; fibrin → fibrinogen fibrinogen; thrombin - fibrin; prothrombin - fibrinogen; thrombin fibrin prothrombin thrombin a) prothrombin fibrinogen fibrin fibrin → thrombin prothrombin Lactate dehydrogenase (LDH) is a classic example of an enzyme regulated by isozymes. The B4 isozyme of LDH uses lactic acid in aerobic conditions to generate a large amount of ATP energy. Which of the following tissues contains predominantly the B4 isozyme? a) b) c) d) skeletal muscle liver white cells heart muscle brain

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