Geneticists isolated six trains of E. coli (strains 1-6) whose lac operons had one of the following mutations (a-f): a. deletion of lacY b. oº mutation c. missense mutation in lacz d. inversion of the lac operon (which does not include the lacl gene) e. superrepressor mutation f. inversion of lacz, Y, and Z, but not lacl, P, o Focusing on the mutation in B: a. what is the state of the lac operon (on, off, inducible, or constitutive)? b. Provide an explanation using repressor, RNA pol, transcription, and the appropriate regulatory region of the operon. c. If a PDNA of another lac operon is inserted into the bacteria with a wild type/normal copy of the DNA, how would this impact the transcription of the original mutant in B?
Geneticists isolated six trains of E. coli (strains 1-6) whose lac operons had one of the following mutations (a-f): a. deletion of lacY b. oº mutation c. missense mutation in lacz d. inversion of the lac operon (which does not include the lacl gene) e. superrepressor mutation f. inversion of lacz, Y, and Z, but not lacl, P, o Focusing on the mutation in B: a. what is the state of the lac operon (on, off, inducible, or constitutive)? b. Provide an explanation using repressor, RNA pol, transcription, and the appropriate regulatory region of the operon. c. If a PDNA of another lac operon is inserted into the bacteria with a wild type/normal copy of the DNA, how would this impact the transcription of the original mutant in B?
Biology (MindTap Course List)
11th Edition
ISBN:9781337392938
Author:Eldra Solomon, Charles Martin, Diana W. Martin, Linda R. Berg
Publisher:Eldra Solomon, Charles Martin, Diana W. Martin, Linda R. Berg
Chapter14: Gene Regulation
Section: Chapter Questions
Problem 9TYU: A mutation that inactivates the repressor gene of the lac operon results in (a) the continuous...
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