Hardy-Weinberg equilibrium. (sickle-cell anemia is recessive) a. What is the frequency of the allele for sickle-cell anemia? b. What is the frequency of the allele for normal hemoglobin? c. What percentage of the population produces only normal hemoglobin? d. What percentage of the population is heterozygous?
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- Which of the following represents an example of qualitative phenotypic variation? a. the lengths of peoples toes b. the body sizes of pigeons c. human ABO blood types d. the birth weights of humans e. the number of leaves on oak trees4.) A man and a woman have a child. The father is blood type A, and one of his parents was blood type A and the other was blood type O. The mother is blood type B, and one of her parents was blood type B, the other type O. Both the father and the mother are carriers of the Bombay allele. (Neither of the type-O grandparents were type O because of the Bombay allele – they had the regular type O genotype.) WhataretheoddsthattheirbabywillhavebloodtypeO? WhataretheoddsthattheirbabywillhavebloodtypeAB? (Hint – for this question, you should draw out a pedigree and fill in as much as you can for the genotypes of BOTH genes that are involved.)9. The factors for normal hemoglobin (S) and sickle-cell hemoglobin (s) are considered codominants: heterozygous individuals have some normal red blood cells and some sickle cells but are not considered to have the disease. A heterozygote is said to have the sickle-cell trait but not the disease. A. What is the genotype of a man with the sickle-cell trait? B. If normal man marries a heterozygous woman, what do you expect for the genotypes and phenotypes of their children? C. If 2 heterozygous people marry and have 3 children who don’t have the disease, what is the chance that their fourth child will have the disease? D. Assume that medical science finds a treatment for sickle-cell anemia so that people with the disease can live out a normal life span but their genes are not changed. If 2 people are saved from the effects of the disease, marry, and have children, what would you expect for the genotypes and phenotypes of their children? Would the children…
- 1. Certain flowers are either red (dominant) or white (rr). 91% of the flowers are red. Using the equations, calculate the frequency of the R allele. First you replace R and r for p and q. Thus we know that q2 = .09, because only the homozygous recessives will be white. *changed away from percentages to work the math more easily* What is the frequency of the R allele in this population? 2. In a coastal city in Nigeria, the incidence of Sickle-Cell disease is 4% of the population. Based on this information, what is the frequency of this allele in the population of that city? 3. In a given human population, only the "A" and "B" alleles are present in the ABO system; there are no individuals with type "O" blood or with O alleles in this particular population. If 200 people have type A blood, 75 have type AB blood, and 25 have type B blood, what are the alleleic frequencies of this population (i.e., what are p and q)? 4. An allele W, for white wool, is dominant over allele w, for…3. A couple just had a baby, who has type-O blood. Upon learning the baby’s blood type, the father becomesinfuriated and accuses the mother of cheating on him. The mother has type-A blood and the father has type-Bblood. Knowing that the allele for type-O is recessive, answer the following questions.a. What is the relationship between the IA, IB, and i alleles?b. Is the father right? Or is he falsely accusing the mother? Explain. Include the genotypes of the parentsand the genotypes of their potential children.5.) A man and a woman living in a tropical area where malaria is prevalent and health care is not accessible have seven children during their lifetime. The genotypes of their children are: ss, Ss, SS, ss, Ss, Ss, and SS. What must the genotypes of both parents be? Your answer should include a Punnett square to illustrate your work, and list all the genotypes and phenotypes.
- 6. Consider that people with blue eyes must have two alleles for blue eyes since blue eye color is a recessive trait. A blue-eyed person and a brown-eyed person have an offspring with blue eyes. The brown-eyed person must A. have two alleles for blue eyes. B. have two alleles for brown eyes. C. not have the dominant brown eye allele. D, have one allele for blue eyes and one allele for brown eyes.3. Researchers are investigating a newly discovered condition that greatly increases the likelihood of lung damage associated with the use of e-cigarettes. They found that 2% of their study population has the condition. The researchers believe they have found a useful marker locus for assessing the presence of the condition in individuals with unknown family history. They have found that, of those individuals with the condition, 99% have the marker allele M1. Of those without the condition, 99.8% have an alternative allele M2 at the marker locus. What is the probability that an individual has the condition if they have marker allele M1 and what do you conclude about the utility of the marker locus for indirect diagnosis?3. A researcher who has been studying albinism has identified a large group of families with four children in which at least one child shows albinism. None of the parents in this group of families shows albinism. Among the children, the ratio of those without albinism to those with albinism is 1.7: 1. The researcher was surprised because he thought that a 3:1 ratio would be expected on the basis of Mendel’s Principle of Segregation. a. As the research keeps increasing his sample of families with four children and at least one of the children with albinism, will the ratio of non-albino children to albino children converge toward the 3:1 ratio that he expects? Why or why not?b. What explains the non-Mendelian segregation ration in the researcher’s present data set?c. If the researcher expands his sample size to 1000 families of four children with at least one albino child, would you expect his data for non-albino vs. albino children to fit a 3:1 ratio if a chi-square test is done for a…
- 2.In dogs, there is a hereditary deafness caused by a recessive allele, d. A kennel owner has a male dog that she wants to use for breeding purposes if possible. The dog can hear, but the owner is unsure of the genotype. She does a testcross (crosses it to a homozygous recessive dog), and two of the five offspring are deaf. This means that the male dog A.has the genotype DD B.has the genotype Dd C.is still of unknown genotype since there were offspring of both deaf and hearing phenotypes. D.has the genotype dd1) Which of the following best describes the different studies/emphases of Mendelians & Biometricians? A. Mendelians emphasized discrete traits caused by heritable variation whereas Biometricians emphasized continuous traits caused by environmental variation. B. Mendelians emphasized discrete traits whereas Biometricians emphasized continuous traits. Both emphasized heritable variation. C. Mendelians emphasized continuous traits caused by heritable variation whereas Biometricians emphasized discrete traits caused by environmental variation. D. Mendelians emphasized discrete traits whereas Biometricians emphasized continuous traits. Both emphasized environmental variation.4. Define the following terms:A. genotype B. phenotype C. monohybrid D. dihybrid5. Distinguish other principles in genetics that do not follow Mendel’s law