Here is my question for you: Protein called p53 is known to have a very important function is cell life and death. There is a gene called p53 that codes for this protein. When the time comes for an old cell to die, this gene gets turned on. It gets transcribed into p53 mRNA, then this mRNA gets translated by ribosomes into the p53 protein, which then gets activated. Once activated, p53 Protein initiates the self-destruction of the old cell. The process of programmed self-destruction of cells is called Apoptosis. Recently, scientists discovered that in cancer cells, the gene coding for p53 protein is mutant (wrong DNA sequence). Step by step describe the consequences of p53 gene mutation: Describe starting from transcription, to translation, to activation, ending with function, how this protein's shape (and function) could come out different/abnormal, after a change in p53 DNA sequence. How can it lead to development of masses of cells (tumors)?

Here is my question for you: Protein called p53 is known to have a very important function is cell life and death. There is a gene called p53 that codes for this protein. When the time comes for an old cell to die, this gene gets turned on. It gets transcribed into p53 mRNA, then this mRNA gets translated by ribosomes into the p53 protein, which then gets activated. Once activated, p53 Protein initiates the self-destruction of the old cell. The process of programmed self-destruction of cells is called Apoptosis. Recently, scientists discovered that in cancer cells, the gene coding for p53 protein is mutant (wrong DNA sequence). Step by step describe the consequences of p53 gene mutation: Describe starting from transcription, to translation, to activation, ending with function, how this protein's shape (and function) could come out different/abnormal, after a change in p53 DNA sequence. How can it lead to development of masses of cells (tumors)?

Human Heredity: Principles and Issues (MindTap Course List)

11th Edition

ISBN:9781305251052

Author:Michael Cummings

Publisher:Michael Cummings

Chapter12: Genes And Cancer

Section: Chapter Questions

Problem 18QP: You are in charge of a new gene therapy clinic. Two cases have been referred to you for review and...

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