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- Give typing answer with explanation and conclusion a) List three eukaryotic gene expression mechanisms that do not occur in prokaryotes. For two of these, give specific examples and the functional outcomes. b) Describe what is meant by the term “RNA silencing”. c) Using diagrams, give two examples of RNA silencing mechanisms and indicate one difference.Explain Termination of transcription by rho specific protein1a. Provide a paper published in a scientific journal between January 2018 and September 2022 that addresses the role of an example of histone modification in affecting expression of a gene by altering histone acetylation/chromatin state of the DNA encoding that gene.
- Explain how the same gen can be highly expressed in several distinct tissues (e.g. brain, liver, and lung) of an organism, yet silent in all other tissues. Hint: The answer is not that they share the same tissue-specific transcription factors..Describe the basic models of transcription factor families, the two transcription factors each representing these models, and how they function molecularly by specifying some of their functions.State whether the gene is up- or down-regulated and briefly explain the reason behind. DNA lacks methylated cytosine residues.
- What are histone proteins, and how are their DNA binding properties regulated. Indicate if there are any modification(s) that comes on and off that regulates how tightly or loosely the Histone proteins are bound to DNA.Name a repressive histone modification (be specific)Give and briefly explain two examples of how gene expression may be repressed without altering the gene-coding sequence.
- Give typing answer with explanation and conclusion Which of the following regions of DNA would you expect to be transcribed. Select all the apply. Marks removed for incorrect selection(s) O a. Enhancer O b. 3' UTR O c. 5' UTR O d. PromoterDescribe the packaging of chromosomal DNA by histones with diagrammatic representations. Name the various histone modifications and describe any two among them.1a. Provide a paper published in a scientific journal between January 2018 and September 2022 that addresses the role of an example of histone modification in affecting expression of a gene by altering histone acetylation/chromatin state of the DNA encoding that gene. What organism and/or cell type did the authors do their study in?