HO CF3 ÕH но Travoprost (pressure inside the eye, including glaucoma) a) Redraw the structure and incorporate suitable modifications or functional group(s) to: i) increase the polarity of the molecule ii) increase the lipophilicity of the molecule

HO CF3 ÕH но Travoprost (pressure inside the eye, including glaucoma) a) Redraw the structure and incorporate suitable modifications or functional group(s) to: i) increase the polarity of the molecule ii) increase the lipophilicity of the molecule

Organic Chemistry

9th Edition

ISBN:9781305080485

Author:John E. McMurry

Publisher:John E. McMurry

Chapter3: Organic Compounds: Alkanes And Their Stereochemistry

Section3.SE: Something Extra

Problem 53AP

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Question

part (ii) please

Travoprost is a drug used to treat the build-up of pressure in the eye. It is
administered as eye drops.
HỌ
CF3
HỖ
ÕH
Travoprost (pressure inside the eye, including glaucoma)
a) Redraw the structure and incorporate suitable modifications or functional group(s)
to:
i) increase the polarity of the molecule
ii) increase the lipophilicity of the molecule
In each case, briefly explain what change(s) you have incorporated and the rationale
behind your structural modification.

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