How does the epithelial-to-mesenchymal transition (EMT) contribute to tumorigenesis and disease progression?

Q: What are Tumor Markers ?

A: Cancer is the abnormal growth and multiplication of normal cells. Cancer cells divide rapidly.…

Q: How is an inmortal cancer cell line different from a regular cancel cell line ?

A: Cancerous cells : In our body cell division and differentiation is a highly regulated and controlled…

Q: What is tumor ? Explain the types of tumor a human can face ?

A: Cell is the basic unit of life. Based on the number of cells an organism may be prokaryotic or…

Q: What is the fastest rate of growth of the tumor?

A: The rate of growth of tumor is slower than expected

Q: What enzyme is upregulated in cancer that overcomes cell senescence?

A: Various type of tumor suppressor genes and oncogenes regulate senescence in normal cell.…

Q: What plays an important role in preventing cancer ?

A: Cancer may be a giant cluster of diseases characterized by the uncontrolled growth and spread of…

Q: What are the normal functions of the BRCA1 tumor suppressor gene?

A: The BRCA1 gene codes for the protein that causes breast cancer type 1. BRCA1 is a human tumour…

Q: What significance do BRCA1 and BRCA2 have in regard to developing cancer, and what types of cancer…

A: BRCA 1 & BRCA 2 are found pair in all the organisms where one gene is obtained from each of the…

Q: What differentiates a benign tumor from a malignant tumor?

A: Step 1 Normal cells remain adhered to one another. They have a definite life span. As some old cell…

Q: What is happening in all cancer? What process is this disrupting?

A: Cancer in simple term can be referred to a set of diseases which are caused by the production of an…

Q: What is the relationship betweenobesity and cancer?

A: Chronic diseases are the leading cause of mortality and morbidity and contribute significantly to…

Q: Why are tumors difficult to treat with drugs?

A: p53 is a gene that makes a protein which is present in the nucleus of a cell  regulates the cell…

Q: Which important characteristic of tumor cells did Otto Warburg discover?

A: Cells are the primary functional unit of life. It divides in number to proceed development in the…

Q: How interfered regulatory machinery results in production of tumor?

A: Eukaryotes have well-organized nucleus. prokaryotes are devoid of nuclear arrangements. genome…

Q: How can oncogenes lead to cancer?

A: Oncogenesis is a complex, multifactorial process by which normal cells turn into malignant cells.…

Q: What is a method some tumors use to evade restriction of their growth by secreting substances that…

A: Cells are the part of human body which grows and divide to make new cells. They are the basic…

Q: What is the difference between a benign and a malignant tumor?

A: The abnormal and uncontrolled division of cells leads to the formation of an undifferentiated mass…

Q: Which cell type(s) below are associated with lysis of tumor cells?

A: Which cell type(s) below are associated with lysis of tumor cells?  Answer. Neutrophils

Q: Which combination of oncogenes, tumor suppressors, and repair enzymes is LEAST likely to develop a…

A: 8. Normally, the human body have controlled cell growth and division i.e. new cells are created to…

Q: What is the role of the microenvironment in cancer development and progression?

A: Progression of cancer is the steps of progress of this disease, it includes many stages:  Stage I…

Q: What is the working of Tumor suppressor genes ?

A: There are two types of genes that are associated with tumors: Oncogenes: These genes when directly…

Q: What genes are involved in cancer?

A: Genes Involved In Cancer --- Genes  and Their Characteristics -- Genes are made up of pieces of DNA…

Q: How do oncogenes differ from tumor suppressor genes?

A: Oncogenes are a physically and functionally diverse set of genes, the protein products of which act…

Q: Why is the tumor microenvironment important to cancer progression?

A: Cancer progression requires metastasis which in turn is the ability of tumors to migrate within the…

Q: Is Epithelial-Mesenchymal Transition (EMT) responsible for invasion and/or metastasis of tumors?…

A: Epithelial - mesenchymal transition is a process in which epithelial cell loss polarity and is…

Q: Why are the tumors not mailgnant?

A: Any unregulation in cell cycle leads to serious consequences like cancer ,apoptosis etc

Q: Under what circumstances is cancer considered to have ahereditary component?

A: The abnormal growth of cells that leads to deleterious effects in the body is referred to as cancer.…

Q: What role do cell check points have in cancer ?

A: Cancer is a disease that is associated with uncontrolled division of cells and invasion of…

Q: What are the heritable changes in cells that contribute to cancer development?

A: Introduction  Cancer is a disease when a few of the body's cells grow out of control and spread to…

Q: What route can breast cancer cells take to escape from the breast to the rest of the body?

A: Cancer is an uncontrolled proliferation of cells in the body that results in accumulation of cell…

Q: How are cells in a biopsy specimen from a tumoridentified as malignant?

A: Diagnostic testing includes procedures that confirm the disease and identify the type of tumor, its…

Q: What properties are gained during tumor progression that contribute to malignant behavior and…

A: The cells normally divide to replace the worn-out cells and died via a process called apoptosis.…

Q: What the hallmarks of cancer are? and briefly explain two of them.

A: The Hallmarks of Cancer are ten anti-cancer defense mechanisms that are hardwired into our cells,…

Q: How tumor-suppressor mutations contribute to cancer?

A: Cancer - Cancer is a type of disease in which cells divide in an uncontrolled manner. The cells…

Q: What are the major differences between a tumor initiator (e.g., DMBA) and a tumor promoting agent…

A: Cancer is a disease in which cells, almost anywhere in the body, begin to divide uncontrollably…

Q: Define tumor progression?

A: Tumorigenesis or carcinogenesis or oncogenesis means the mechanism of induction of tumors; agents…

Q: What are the most common treatments of cancer?

A: Introduction: Uncontrolled cell division is a symptom of cancer. Tumors, immune system harm, and…

Q: How might overexpression of proto-oncogenes lead to abnormal cellular proliferation?

A: A proto-oncogene is a cell's normal gene. Proto-oncogenes are plentiful. Each one is in charge of…

Q: What advantage do iPS cells have over traditional embryonic stem cells?

A: Induced pluripotent cells (iPS) are somatic  cells that have been reconstructed to act like an ES…

Q: What characteristics are shown by cancer cells?

A: Cancer or tumor cells are the cells that have lost the property of controlled growth and development…

Q: What is haploinsufficiency? How might it affect cancer risk?

A: The term in genetics that explains the function of the dominant gene in the representation of…

Q: What is the difference between benign and malignant tumors? What is the disadvantage of this…

A: TUMOR- A tumor is a lump or growth of cells that is abnormal. A tumor can sometimes be made up of…

Q: Describe the genetic changes that convert proto-oncogenesinto oncogenes or inactivate…

A: Oncogenes can be defined as the genes which induce cancer in the organisms. These genes encode the…

Q: What are the key steps of transformation, tumorigenesis and metastasis on a cellular and tissue…

A: Transformation is a process in which a normal cell is transform into a cancerous cell  Tumor genesis…

Genomic studies

Genomic studies (genomics) is the study of the whole genome of an organism. Using bioinformatics and high-performance computing, genomic researchers examined massive amounts of deoxyribonucleic acid (DNA)-sequence data to discover variations or mutations that affect drug response, health, or disease. Genomics is a much younger discipline than genetics, having only emerged in the last few decades as a result of technological advancements in DNA sequencing and computational biology.