What significance do BRCA1 and BRCA2 have in regard to developing cancer, and what types of cancer are associated with these genes?

Human Heredity: Principles and Issues (MindTap Course List)
11th Edition
ISBN:9781305251052
Author:Michael Cummings
Publisher:Michael Cummings
Chapter12: Genes And Cancer
Section12.10: Genomics, Epigenetics,and Cancer
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What significance do BRCA1 and BRCA2 have in regard to developing cancer, and what types of cancer are associated with these genes?

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BRCA 1 & BRCA 2 are found pair in all the organisms where one gene is obtained from each of the parent.

These gene are of great significance as these are the genes which are responsible for inhibiting the formation or development of cancer in a cell.

They are helpful in oncogenic transformation of a cell, they are related with the repair of damaged DNA due to any mutation and are act as mediator of the homologous recombination between Chromosomes.

 thus these genes are called as tumour suppressing gene.

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