How reliable are Lateral flowimmunochromatographic assays when compared to molecular diagnostic tests or other serological tests? Please discuss referring to original articles example of covid 19..
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- Explain the statistical findings regarding the lateral flowimmunochromatographic assays sensitivity and robustness when compared to other test methods? Please discuss refering to original articles as examples Covid 19.There are many immunotherapeutics now being used to immunomodulate recipients that are either fully human monoclonal antibodies or partially humanized monoclonal antibodies. Discuss whether or not they may interfere with solid phase antibody assays, CDC assays or cell based flow cytometry crossmatches.please help explain would SARS-CoV-2 N-nucleocasid protein be good target for neutralizing antibodies and vaccine development ?and why
- Briefly discuss how Enzyme-linked immunosorbent assay (ELISA) and western blotting contributeto immunological testing.What is the working principle of Lateral flowimmunochromatographic assays (LFIAs)? Supported with a figure and reference plzOutline the principle behind the following techniques: 1. Immunofixation 2. Southern blotting 3. Ion exchange chromatograph 4. SDS-PAGE.
- Following SDS-PAGE, what is an advantage of protein detection by immunoblotting (western blotting) over a non-specific gel-staining procedure? Under what circumstances would it be desirable to nonspecifically stain the gel, rather than immunoblotting?EIAs are extremely sensitive diagnostic tools. Why,then, is the immunoblot (Western blot) procedure usedto confirm screening tests that are positive for humanimmunodeficiency virus (HIV)?explain or describe the principle of immunoturbidimetric C3 Assay.
- What are the advantages/disadvantages of using a direct immunoblotting method? Compare and contrast to an indirect immunoblotting method.Define the principle immunoturbidimetric C3 assayHow we can Treatment Severe Combined Immunodeficiency (SCID) by using gene therapy? Please answer at your own words,please..