HOW TO SOLVE THIS IN EXCEL? For the following aspartate reaction in the presence of inhibitor, Km = 0.00065 M. Determine Vmax in both reactions and in the reaction without inhibitor, the Km. Identify whether the inhibition is competitive, non-competitive or uncompetitive. ( see attached picture ) Briefly explain: how I and S bind to the E as shown by the Lineweaver Burk plot.  the significance of the following obtained values for Km and Vmax.  effect in slope and x-intercept

Essentials of Pharmacology for Health Professions
7th Edition
ISBN:9781305441620
Author:WOODROW
Publisher:WOODROW
Chapter5: Abbreviations And Systems Of Measurement
Section: Chapter Questions
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HOW TO SOLVE THIS IN EXCEL?

For the following aspartate reaction in the presence of inhibitor, Km = 0.00065 M. Determine Vmax in both reactions and in the reaction without inhibitor, the Km. Identify whether the inhibition is competitive, non-competitive or uncompetitive. ( see attached picture )

Briefly explain:

    • how I and S bind to the E as shown by the Lineweaver Burk plot. 
    • the significance of the following obtained values for Km and Vmax. 
    • effect in slope and x-intercept
110
1/V a
1/V
50-
40-
30
0000
0009
000-
000,
Transcribed Image Text:110 1/V a 1/V 50- 40- 30 0000 0009 000- 000,
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